1H-Imidazole-1-ethanol, 2-methyl-5-nitro-, hydrochloride
Synonyms
Metronidazole HCl;
Metronidazole hydrochloride;
Imidazole-1-ethanol, 2-methyl-5-nitro-, hydrochloride;
Category
Non-ionic surfactant
> Amine
>> Heteroaromatic Amine
>>> Imidazole and its Derivatives
Chemical Numbering System
CASRN: 69198-10-3
EINECS: N/A
Molecular Formula & Molecular Weight
Molecular Formula: C6H10ClN3O3; C6H9N3O3.HCl
Molecular Weight: 207.61
Structure
Properties
Appearance (1), solid.
Solubility soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2, nitrogen oxides and so on. Contact with strong oxidants, can cause to burn.
GHS (Rev.10) label: 
Human Toxicity
Table 1 Human toxicity values
|
child intravenous TDLo |
200mg/kg/90H[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent antimicrobial, anti-infective, antiprotozoal abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as antibacterial agent, antiprotozoal agent.
Manufacturers
References
[1]: ChemIDplus. 69198-10-3, Metronidazole hydrochloride