Imidazole
Synonyms
1H-Imidazole;
1,3-Diaza-2,4-cyclopentadiene;
1,3-Diazole;
Category
Non-ionic surfactant
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>> Heteroaromatic Amine
>>> Imidazole and its Derivatives
Chemical Numbering System
CASRN: 288-32-4
EINECS: 206-019-2
Molecular Formula & Molecular Weight
Molecular Formula: C3H4N2
Molecular Weight: 68.08
Structure
Properties
Appearance (1), white crystal.
Solubility soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2, nitrogen oxides and so on. Contact with strong oxidants, can cause to burn.
GHS (Rev.10) label: 
Animal Toxicity
Table 1 Animal toxicity values
|
cat subcutaneous LDLo |
125mg/kg[1] |
|
dog subcutaneous LD50 |
28mg/kg[1] |
|
guinea pig oral LD50 |
760mg/kg[1] |
|
mouse intraperitoneal LD50 |
300mg/kg[1] |
|
mouse intravenous LD50 |
475mg/kg[1] |
|
mouse oral LD50 |
880mg/kg[1] |
|
mouse subcutaneous LD50 |
817mg/kg[1] |
|
rat oral LD50 |
220mg/kg[1] |
|
rat subcutaneous LD50 |
626mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent dispersing, emulsifying abilities. Imidazole has alkalinity, the 3-position nitrogen atom has more basic; also has acidity, can react with strong base to form salt. Not to be used in personal care products.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as buffering agent.
Used in organic synthesis.
Manufacturers
References
[1]: ChemIDplus. 288-32-4, Imidazole