Imidazole
Time: 2022-10-25 12:11:15; Reading: 0

Imidazole

Synonyms

1H-Imidazole;

1,3-Diaza-2,4-cyclopentadiene;

1,3-Diazole;

Category

Non-ionic surfactant

> Amine

>> Heteroaromatic Amine

>>> Imidazole and its Derivatives

Chemical Numbering System

CASRN: 288-32-4

EINECS: 206-019-2

Molecular Formula & Molecular Weight

Molecular Formula: C3H4N2

Molecular Weight: 68.08

Structure

Properties

Appearance    (1), white crystal.

Solubility    soluble in water.

Stability    stable.

Risk    Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2, nitrogen oxides and so on. Contact with strong oxidants, can cause to burn.

GHS (Rev.9) label:  

Animal Toxicity

Table 1 Animal toxicity values

cat subcutaneous LDLo

125mg/kg[1]

dog subcutaneous LD50

28mg/kg[1]

guinea pig oral LD50

760mg/kg[1]

mouse intraperitoneal LD50

300mg/kg[1]

mouse intravenous LD50

475mg/kg[1]

mouse oral LD50

880mg/kg[1]

mouse subcutaneous LD50

817mg/kg[1]

rat oral LD50

220mg/kg[1]

rat subcutaneous LD50

626mg/kg[1]

Ecology    may be hazardous to environment. Water body should be given special attention.

Biodegradability    biodegradable.

Characteristics    excellent dispersing, emulsifying abilities. Imidazole has alkalinity, the 3-position nitrogen atom has more basic; also has acidity, can react with strong base to form salt. Not to be used in personal care products.

Synthesis

 

Quality Standards & Test Methods

1, Physical and chemical indexes

Item

Physical and chemical indexes

Solid

Actives, %, ≥

95.0

Test Methods

(1), Actives

GB/T 13173 Surface active agents -- Detergents -- Testing methods

2, Hazardous substances indexes

Item

Hazardous substances indexes

Solid

Heavy metals (as Pb), mg/kg, ≤

20

As, mg/kg, ≤

3

Test Methods

(1), Heavy metals (as Pb)

Safety and Technical Standards for Cosmetics (2015 Edition)

GB/T 30799 The test method of food detergents -- Determination of heavy metals

(2), As

Safety and Technical Standards for Cosmetics (2015 Edition)

GB/T 30797 The test method of food detergents -- Determination of total arsenic

3, Further explanation

(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.

Major Uses

1, Typical applications

Use as buffering agent.

Used in organic synthesis.

Manufacturers

 

References

[1]: ChemIDplus. 288-32-4, Imidazole