Meroxapol
Synonyms
Block polyethylene-polypropylene glycol;
Block polyoxyethylene-polyoxypropylene;
Oxirane, methyl-, polymer with oxirane, block;
Polyoxyethylene - polyoxypropylene block copolymer;
Reverse polyoxyethylene - polyoxypropylene block copolymer;
Category
Non-ionic surfactant
> Polyether
>> Ethylene Oxide - Propylene Oxide Homopolymer and Copolymer
Chemical Numbering System
CASRN: 9003-11-6
EINECS: N/A
Molecular Formula & Molecular Weight
Molecular Formula: N/A
Molecular Weight: N/A
Structure
Properties
Appearance (1), colorless transparent liquid to white paste to white solid.
Solubility insoluble in water to soluble in water. Soluble in ethanol, toluene. Solubility is related to EO number, PO number.
Stability stable.
Risk Liquid (or solid) form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS (Rev.10) label: 
Animal Toxicity
Table 1 Animal toxicity values
|
mouse intravenous LD50 |
175mg/kg[1] |
|
mouse intravenous LDLo |
6000mg/kg[1] |
|
mouse oral LD50 |
3000mg/kg[1] |
|
mouse oral LD50 |
> 15000mg/kg[1] |
|
mouse oral LD50 |
45000mg/kg[1] |
|
mouse oral LDLo |
15000mg/kg[1] |
|
mouse intraperitoneal LDLo |
5000mg/kg[1] |
|
rabbit oral LD50 |
35000mg/kg[1] |
|
rat inhalation LC50 |
320mg/m3/4H[1] |
|
rat oral LD50 |
5700mg/kg[1] |
|
rat oral LDLo |
16000mg/kg[1] |
|
rat intraperitoneal LDLo |
10000mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent cleansing, emulsifying, dispersing, solubilizing, lubricating, antistatic, antifoaming, demulsifying abilities. Performance is related to EO number, PO number. Low foaming. Resistance to non-oxidative acid.
Note (1), The by-product 1,4-dioxane is a possible carcinogen. Generally, can be acceptable when concentration of 1,4-dioxane is less than 30ppm or less.
(2), Be careful with using in children's products.
(3), Meroxapol naming rule:
The first two digits in a three-digit number, multiplied by 100, indicates the approximate molecular weight of the hydrophobic part (PO). The last digit, multiplied by 10, indicates the approximate content of hydrophilic part (EO).
(4), The properties of PPG terminated block polyether and PEG terminated block polyether are quite different. Generally, PPG terminated block polyether has higher surface tension.
Synthesis
Obtained by polymerization of ethylene oxide and methyloxirane.
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Liquid/paste/solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Liquid/paste/solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as cleansing agent.
Use as emulsifying agent, dispersing agent.
Use as solubilizing agent.
Use as lubricant.
Use as antifoaming agent.
2, Personal care products
Emulsifying agent, cleansing agent in personal care products.
3, Agriculture
Emulsifying agent in pesticide.
Product members
Meroxapol 105;
Meroxapol 108;
Meroxapol 171;
Meroxapol 172;
Meroxapol 174;
Meroxapol 178;
Meroxapol 251;
Meroxapol 252;
Meroxapol 254;
Meroxapol 255;
Meroxapol 258;
Meroxapol 311;
Meroxapol 312;
Meroxapol 314;
Manufacturers
References
[1]: ChemIDplus. 9003-11-6, Polyethylene-polypropylene glycol