Polysorbate 21
Time: 2019-12-22 22:44:08

Polysorbate 21

Synonyms

Polyethylene glycol (4) sorbitan monolaurate;

PEG-4 Sorbitan laurate;

Polyoxyethylene (4) sorbitan monolaurate;

Tween 21;

Category

Non-ionic surfactant

> Polyether

>> Ester Polyether

>>> Ester Polyoxyethylene Ether

>>>> Polyoxyethylene Sugar Alcohol and Dehydrated Sugar Alcohol Esters

Chemical Numbering System

CASRN: 9005-64-5

EINECS: 500-018-3

Molecular Formula & Molecular Weight

Molecular Formula: N/A

Molecular Weight: N/A

Structure

Schematic formula:

Properties

Appearance    (1), colorless to yellow-brown liquid.

Solubility    soluble in water.

Stability    stable. Under strong acid or strong alkali condition, easily hydrolyzed.

Risk    Liquid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.

GHS (Rev.7) label:  

Animal Toxicity

Table 1 Animal toxicity values

hamster oral LD50

18mL/kg[1]

mouse intraperitoneal LD50

2640mg/kg[1]

mouse intravenous LD50

1420mg/kg[1]

mouse oral LD50

> 33000mg/kg[1]

rat intraperitoneal LD50

3850mg/kg[1]

rat intravenous LD50

770mg/kg[1]

rat oral LD50

36.7mL/kg[1]

Ecology    may be hazardous to environment. Water body should be given special attention.

Biodegradability    biodegradable.

Characteristics    excellent emulsifying, dispersing, solubilizing, lubricating abilities.

Note    (1), The by-product 1,4-dioxane is a possible carcinogen. Generally, can be acceptable when concentration of 1,4-dioxane is less than 30ppm or less.

(2), Be careful with using in children's products.

Synthesis

 

Quality Standards & Test Methods

1, Physical and chemical indexes

Item

Physical and chemical indexes

Liquid

Actives, %, ≥

95.0

Test Methods

(1), Actives

GB/T 13173 Surface active agents -- Detergents -- Testing methods

2, Hazardous substances indexes

Item

Hazardous substances indexes

Liquid

Heavy metals (as Pb), mg/Kg, ≤

20

As, mg/Kg, ≤

3

Test Methods

(1), Heavy metals (as Pb)

Safety and Technical Standards for Cosmetics (2015 Edition)

GB/T 30799 The test method of food detergents -- Determination of heavy metals

(2), As

Safety and Technical Standards for Cosmetics (2015 Edition)

GB/T 30797 The test method of food detergents -- Determination of total arsenic

3, Further explanation

(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.

(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.

Major Uses

1, Typical applications

Use as emulsifying agent, dispersing agent.

Use as solubilizing agent.

Use as lubricant.

Use as plasticizer.

2, Personal care products

Emulsifying agent in personal care products.

3, Textile

Antistatic agent, emulsifying agent in fiber, textile, leather.

4, Polymer

Lubricant in plastics.

5, Machinery

Lubricant in metal processing.

Manufacturers

 

References

[1]: ChemIDplus. 9005-64-5, Polyoxyethylene sorbitan monolaurate