Repagermanium
Synonyms
Propagermanium；
Poly-trans-((2-Carboxyethyl) Germasesquioxane);
Category
Special Surfactant
> Organogermanium
>> Anionic-type Organogermanium
>>> Carboxyalkyl Organogermanium
>>>> Carboxyl Linear Alkyl Organogermanium
Chemical Numbering System
CASRN：12758-40-6
EINECS：235-800-0
Molecular Formula & Molecular Weight
Molecular Formula: ((HOOCCH2CH2Ge)2O3)n
Molecular Weight: N/A
Structure
Properties
Appearance (1), solid.
Solubility soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS (Rev.10) label: 
Animal Toxicity
Table 1 Animal toxicity values
|
dog oral LD |
> 4000mg/kg[1] |
|
mouse intraperitoneal LD50 |
1250mg/kg[1] |
|
mouse intravenous LD50 |
> 200mg/kg[1] |
|
mouse oral LD50 |
5600mg/kg[1] |
|
mouse subcutaneous LD50 |
> 4000mg/kg[1] |
|
rat intraperitoneal LD50 |
1670mg/kg[1] |
|
rat intravenous LD50 |
> 200mg/kg[1] |
|
rat oral LD50 |
7050mg/kg[1] |
|
rat subcutaneous LD50 |
> 4000mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent antineoplastic, emulsifying, dispersing abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents - Detergents - Testing methods
GB/T 5173 Surface active agents and detergents－Determination of anionic-active matter by direct two-phase titration procedure
ISO 2271 Surface active agents -- Detergents -- Determination of anionic-active matter by manual or mechanical direct two-phase titration procedure
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/Kg, ≤ |
20 |
|
As, mg/Kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents - Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents - Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances; or furtherly test for microorganisms.
Major Uses
1, Typical applications
Use as pharmaceutical ingredient.
2, Personal care products
Conditioning agent in personal care products.
3, Medicine
Use as pharmaceutical ingredient. (This section is for reference only, should be implemented according to local Pharmacopoeia.)
Manufacturers
References
[1]: ChemIDplus. 12758-40-6, Propagermanium