Menadione sodium bisulfite trihydrate
Synonyms
Menadione sodium bisulfite;
2-Naphthalenesulfonic acid, 1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-, sodium salt, trihydrate;
Category
Anionic Surfactant
> Sulfonate
>> Quinonyl Sulfonate
>>> Naphthoquinonyl Sulfonate
>>>> Linear alkyl Naphthoquinonyl Sulfonate
Chemical Numbering System
CASRN：6147-37-1
EINECS：N/A
Molecular Formula & Molecular Weight
Molecular Formula: C11H15NaO8S; C11H10O5S.Na.3H2O
Molecular Weight: 330.29
Structure
Properties
Appearance (1), solid.
Solubility soluble in water.
Stability stable. Light is easy to break down.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS (Rev.10) label: 
Animal Toxicity
Table 1 Animal toxicity values
|
rat oral LD50 |
4507mg/kg[1] |
|
rat intraperitoneal LD50 |
985mg/kg[1] |
|
rat intravenous LD50 |
800mg/kg[1] |
|
mouse intraperitoneal LD50 |
384mg/kg[1] |
|
mouse oral LD50 |
1570mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent wetting, dispersing abilities.
Synthesis
2-Methylnaphthoquinone reacts with sodium sulfite, then obtain.
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
60.0 |
|
pH (25°C, 1% solution) |
< 6.0 |
Test Methods
(1), Actives
Chinese Pharmacopoeia (2015 Edition) Menadione sodium bisulfite
(2), pH
GB/T 6368 Surface active agents - Determination of pH of aqueous solution - Potentiometric method
ISO 4316 Surface active agents -- Determination of pH of aqueous solutions -- Potentiometric method
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/Kg, ≤ |
20 |
|
As, mg/Kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents - Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents - Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), Chinese Pharmacopoeia (2015 Edition) Menadione sodium bisulfite
(1b), GB 7294 Feed additive - Vitamin K3 (menadione sodium bisulfite)
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Medicine
Use as Use as pharmaceutical ingredient(Vitamin). (This section is for reference only, used in medicine, must comply with local pharmacopoeia execution.)
2, Feed
Use as feed additive.
Manufacturers
References
[1]: ChemIDplus. 6147-37-1, Menadione sodium bisulfite