Clonixin
Synonyms
3-Pyridinecarboxylic acid, 2-((3-chloro-2-methylphenyl)amino)-;
Nicotinic acid, 2-(3-chloro-o-toluidino)-;
Category
Zwitterionic Surfactant
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Chemical Numbering System
CAS: 17737-65-4
EINECS: 241-730-1
Molecular Formula & Molecular Weight
Molecular Formula: C13H11ClN2O2; C13H11Cl1N2O2
Molecular Weight: 262.69
Structure
Properties
Appearance (1), solid.
Solubility insoluble in water.
Stability stable.
Risk Solid form: irritation, irritation to skin, eye, respiratory system.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
mouse intraperitoneal LD50 |
198mg/kg[1] |
|
mouse oral LD50 |
400mg/kg[1] |
|
mouse subcutaneous LD50 |
263mg/kg[1] |
|
rat intraperitoneal LD50 |
148mg/kg[1] |
|
rat oral LD50 |
335mg/kg[1] |
|
rat subcutaneous LD50 |
325mg/kg[1] |
Reproductive effect[1].
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent analgesic, anti-inflammatory, emulsifying, dispersing abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as UV absorbing agent.
Use as pharmaceutical ingredient. (For reference only.)
Manufacturers
References
[1]: ChemIDplus. 17737-65-4, Clonixin
Update: 20190428(1);