Dihydroergocristine mesylate
Synonyms
Ergocristine, 9,10-dihydro-, monomethanesulfonate (salt);
Ergotamane-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-(1-methylethyl)-5'-(phenylmethyl)-, (5'-alpha,10-alpha)-, monomethanesulfonate (salt);
Category
Non-ionic surfactant
> Amine
>> Heteroaromatic Amine
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Chemical Numbering System
CAS: 24730-10-7
EINECS: 246-434-6
Molecular Formula & Molecular Weight
Molecular Formula: C36H45N5O8S; C35H41N5O5.C1H4O3S
Molecular Weight: 707.84
Structure
Properties
Appearance (1), solid.
Solubility slightly soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2, nitrogen oxides and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
dog intravenous LD50 |
> 50mg/kg[1] |
|
dog oral LD50 |
> 1250mg/kg[1] |
|
mouse intraperitoneal LD50 |
120mg/kg[1] |
|
mouse intravenous LD50 |
70mg/kg[1] |
|
mouse oral LD50 |
> 2500mg/kg[1] |
|
rat intraperitoneal LD50 |
585mg/kg[1] |
|
rat intravenous LD50 |
91mg/kg[1] |
|
rat oral LD50 |
2643mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent antistatic, dispersing, emulsifying abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as pharmaceutical ingredient.
Manufacturers
References
[1]: ChemIDplus. 24730-10-7, Dihydroergocristine mesylate
Update: 20200905(1);