Kanamycin A
Synonyms
Kanamycin;
D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1-4))-2-deoxy-;
Category
Non-ionic surfactant
> Sugar-type
>> Aminosaccharide and its Derivatives
Chemical Numbering System
CAS: 59-01-8
EINECS: 200-411-7
Molecular Formula & Molecular Weight
Molecular Formula: C18H36N4O11
Molecular Weight: 484.50
Structure
Properties
Appearance (1), solid.
Solubility soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2, nitrogen oxide and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
mouse intramuscular LD50 |
54mg/kg[1] |
|
mouse intraperitoneal LD50 |
794mg/kg[1] |
|
mouse intravenous LD50 |
115mg/kg[1] |
|
mouse oral LD50 |
20.7mg/kg[1] |
|
mouse subcutaneous LD50 |
1350mg/kg[1] |
|
rat intramuscular LD50 |
> 1014mg/kg[1] |
|
rat intraperitoneal LD50 |
1515mg/kg[1] |
|
rat intravenous LD50 |
437mg/kg[1] |
|
rat oral LD50 |
> 10000mg/kg[1] |
|
rat subcutaneous LD50 |
4070mg/kg[1] |
|
guinea pig intraperitoneal LD50 |
1385mg/kg[1] |
|
rabbit intravenous LD50 |
150mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent antimicrobial, antibacterial, antistatic abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as antimicrobial agent, antibacterial agent.
Manufacturers
References
[1]: ChemIDplus. 59-01-8, Kanamycin
Update: 20190929(1)