Cephalexin
Synonyms
Cefalexin;
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-(((2R)-aminophenylacetyl)amino)-3-methyl-8-oxo-, (6R,7R)-;
Category
Zwitterionic Surfactant
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Chemical Numbering System
CAS: 15686-71-2
EINECS: 239-773-6
Molecular Formula & Molecular Weight
Molecular Formula: C16H17N3O4S
Molecular Weight: 347.39
Structure
Properties
Appearance (1), white to slightly yellow solid.
Solubility slightly soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
cat intraperitoneal LDLo |
1000mg/kg[1] |
|
cat oral LDLo |
250mg/kg[1] |
|
dog oral LD |
> 1000mg/kg[1] |
|
dog intraperitoneal LD50 |
> 1000mg/kg[1] |
|
guinea pig intraperitoneal LDLo |
1000mg/kg[1] |
|
guinea pig oral LDLo |
5000mg/kg[1] |
|
monkey oral LDLo |
> 1000mg/kg[1] |
|
mouse intraperitoneal LD50 |
400mg/kg[1] |
|
mouse oral LD50 |
1495mg/kg[1] |
|
mouse subcutaneous LD50 |
1150mg/kg[1] |
|
rabbit intraperitoneal LDLo |
> 4000mg/kg[1] |
|
rabbit oral LDLo |
2500mg/kg[1] |
|
rat intraperitoneal LD50 |
4000mg/kg[1] |
|
rat oral LD50 |
> 20000mg/kg[1] |
|
rat subcutaneous LD50 |
6100mg/kg[1] |
Reproductive effect[1].
Human Toxicity
Table 2 Human toxicity values
|
human oral TDLo |
14mg/kg/D[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent antimicrobial, antibacterial, anti-infective, preservative abilities. beta-Lactam antibiotic, cephalosporins.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as antibacterial agent.
Use as pharmaceutical ingredient (antibiotic).
Manufacturers
References
[1]: ChemIDplus. 15686-71-2, Cephalexin
Update: 20190414(1);