Styrene methyltrimonium chloride crosspolymer
Synonyms
Cholestyramine resin;
Cholestyramine;
Category
Cationic surfactant
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Chemical Numbering System
CAS: 11041-12-6
EINECS: 234-270-8
Molecular Formula & Molecular Weight
Molecular Formula: N/A
Molecular Weight: N/A
Structure
Properties
Appearance (1), solid.
Solubility insoluble in water. The solubility is related to crosslinking degree.
Stability stable.
Risk Solid form: irritation, irritation to skin, eye.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
mouse intraperitoneal LD50 |
> 4000mg/kg[1] |
|
mouse oral LD50 |
> 7500mg/kg[1] |
|
mouse subcutaneous LD50 |
> 3000mg/kg[1] |
|
rabbit oral LD50 |
> 3000mg/kg[1] |
|
rat intraperitoneal LD50 |
> 1600mg/kg[1] |
|
rat oral LD50 |
> 4000mg/kg[1] |
|
rat subcutaneous LD50 |
> 1200mg/kg[1] |
Reproductive effect[1].
Human Toxicity
Table 2 Human toxicity values
|
child oral TDLo |
46000mg/kg/39W-I[1] |
|
infant oral TDLo |
4000mg/kg/2D-I[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent antistatic, emulsifying, dispersing, film-forming abilities. Crosslinking agent: divinylbenzene.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as antistatic agent.
Use as flocculant.
Use as film-forming agent.
2, Personal care products
Absorbent in personal care products.
3, Water treatment
Use as strong basic type anion exchange resin.
4, Medicine
Use as pharmaceutical ingredient. (This section is for reference only, should be implemented according to local Pharmacopoeia.)
Manufacturers
References
[1]: ChemIDplus. 11041-12-6, Cholestyramine resin
Update: 20190617(1);