Floctafenine
Synonyms
Benzoic acid, 2-((8-(trifluoromethyl)-4-quinolinyl)amino)-, 2,3-dihydroxypropyl ester;
Category
Non-ionic surfactant
> Amine
>> Heteroaromatic Amine
>>> Quinoline and its Derivatives
Chemical Numbering System
CAS: 23779-99-9
EINECS: 245-881-4
Molecular Formula & Molecular Weight
Molecular Formula: C20H17F3N2O4
Molecular Weight: 406.36
Structure
Properties
Appearance (1), solid.
Solubility slightly soluble in water.
Stability stable.
Risk Solid form: irritation, irritation to skin, eye, respiratory system.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
dog oral LD50 |
> 1000mg/kg[1] |
|
mouse intraperitoneal LD50 |
245mg/kg[1] |
|
mouse intravenous LD50 |
180mg/kg[1] |
|
mouse oral LD50 |
1960mg/kg[1] |
|
mouse subcutaneous LD50 |
> 4000mg/kg[1] |
|
rabbit oral LD50 |
700mg/kg[1] |
|
rat intraperitoneal LD50 |
250mg/kg[1] |
|
rat intravenous LD50 |
160mg/kg[1] |
|
rat oral LD50 |
535mg/kg[1] |
|
rat subcutaneous LD50 |
> 4000mg/kg[1] |
Reproductive effect[1].
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent anti-inflammatory, analgesic, dispersing, antistatic abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as pharmaceutical ingredient (analgesic) (For reference only.).
Manufacturers
References
[1]: ChemIDplus. 23779-99-9, Floctafenine
Update: 20200830(1);