Thiophanate-methyl
Synonyms
Thiophanate methyl;
Carbamic acid, (1,2-phenylenebis(iminocarbonothioyl))bis-, dimethyl ester;
Category
Non-ionic surfactant
> Ester
>> Allophanic Acid Ester
Chemical Numbering System
CAS: 23564-05-8
EINECS: 245-740-7
Molecular Formula & Molecular Weight
Molecular Formula: C12H14N4O4S2
Molecular Weight: 342.39
Structure
Properties
Appearance (1), solid.
Solubility slightly soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
dog oral LDLo |
4000mg/kg[1] |
|
guinea pig oral LD50 |
3640mg/kg[1] |
|
guinea pig skin LD50 |
> 10000mg/kg[1] |
|
mouse oral LD50 |
3400mg/kg[1] |
|
mouse skin LD50 |
> 10000mg/kg[1] |
|
quail skin LD50 |
> 5000mg/kg[1] |
|
rabbit oral LD50 |
2270mg/kg[1] |
|
rabbit skin LD50 |
> 10000mg/kg[1] |
|
rat inhalation LC50 |
1700mg/m3/4H[1] |
|
rat intraperitoneal LD50 |
1140mg/kg[1] |
|
rat oral LD50 |
6640mg/kg[1] |
|
rat skin LD50 |
> 10000mg/kg[1] |
Reproductive effect[1].
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent antimicrobial, antibacterial abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), GB/T 23552 Thiophanate-methyl wettable powders
(1b), GB/T 24755 Thiophanate-methyl technical
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as antibacterial agent.
2, Agriculture
Use as antibacterial agent.
Manufacturers
References
[1]: ChemIDplus. 23564-05-8, Thiophanate-methyl
Update: 20200524(1);