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Clindamycin

Time: 2015-04-14 17:27:40; Count: 5

Clindamycin

Synonyms

L-threo-alpha-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(((1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-, (2S-trans)-;

Category

Non-ionic surfactant

> Sugar-type

>> Glycoside

Chemical Numbering System

CAS: 18323-44-9

EINECS: 242-209-1

Molecular Formula & Molecular Weight

Molecular Formula: C18H33ClN2O5S; C18H33Cl1N2O5S

Molecular Weight: 424.98

Structure

Properties

Appearance    (1), solid.

Solubility    slightly soluble in water.

Stability    stable.

Risk    Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.

GHS label:  

Animal Toxicity

Table 1 Animal toxicity values

hamster oral LDLo

1mg/kg[1]

rabbit oral LDLo

1mg/kg[1]

rat subcutaneous LD50

2618mg/kg[1]

Ecology    may be hazardous to environment. Water body should be given special attention.

Biodegradability    biodegradable.

Characteristics    excellent antimicrobial, antibacterial abilities.

Synthesis

 

Quality Standards & Test Methods

1, Physical and chemical indexes

Item

Physical and chemical indexes

Solid

Actives, %, ≥

95.0

Test Methods

(1), Actives

GB/T 13173 Surface active agents -- Detergents -- Testing methods

2, Hazardous substances indexes

Item

Hazardous substances indexes

Solid

Heavy metals (as Pb), mg/kg, ≤

20

As, mg/kg, ≤

3

Test Methods

(1), Heavy metals (as Pb)

Safety and Technical Standards for Cosmetics (2015 Edition)

GB/T 30799 The test method of food detergents -- Determination of heavy metals

(2), As

Safety and Technical Standards for Cosmetics (2015 Edition)

GB/T 30797 The test method of food detergents -- Determination of total arsenic

3, Further explanation

(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.

Major Uses

1, Typical applications

Use as antimicrobial agent, antibacterial agent.

Manufacturers

 

References

[1]: ChemIDplus. 18323-44-9, Clindamycin

Update: 20191014(1)

Article

[Terminology] Dispersion system

[Terminology] Vesicle

Pandect of Ester surfactants (1): Definition

[Terminology] Van Der Waals force

[Terminology] Micellar aggregation number

Standard

Test methods of surfactants, catalog, Chinese national standards

Surfactants, catalog, Chinese national standards