Dimethyl fumarate
Synonyms
2-Butenedioic acid (E)-, dimethyl ester;
Fumaric acid, dimethyl ester;
Category
Non-ionic surfactant
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Chemical Numbering System
CAS: 624-49-7
EINECS: 210-849-0
Molecular Formula & Molecular Weight
Molecular Formula: C6H8O4
Molecular Weight: 144.13
Structure
Properties
Appearance (1), solid.
Solubility soluble in water.
Stability stable. Under strong acid or strong alkali condition, easily hydrolyzed. Easily oxidized.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
mouse inhalation LC |
> 3100mg/m3/10[1] |
|
rabbit skin LD50 |
1250mg/kg[1] |
|
rat oral LD50 |
2240mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent antimicrobial, antibacterial, preservative, film-forming, dispersing abilities. Contact with skin, can cause allergy.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as monomer.
Use as film-forming agent.
Use as antimicrobial agent, preservative.
Manufacturers
References
[1]: ChemIDplus. 624-49-7, Dimethyl fumarate
Update: 20200614(1);