Triethylene glycol
Synonyms
2,2'-(Ethylenedioxy)diethanol;
TEG;
Category
Non-ionic surfactant
> Polyether
>> Ethylene Oxide - Propylene Oxide Homopolymer and Copolymer
Chemical Numbering System
CAS: 112-27-6
EINECS: 203-953-2
Molecular Formula & Molecular Weight
Molecular Formula: C6H14O4
Molecular Weight: 150.17
Structure
Properties
Appearance (1), colorless transparent liquid.
Solubility soluble in water.
Stability stable.
Risk Liquid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
rabbit skin LD50 |
> 20mL/kg[1] |
|
rabbit intravenous LD50 |
1900mg/kg[1] |
|
rabbit oral LD50 |
8400mg/kg[1] |
|
dog intravenous LD50 |
> 4500mg/kg[1] |
|
guinea pig intravenous LD50 |
10600mg/kg[1] |
|
guinea pig oral LD50 |
7900mg/kg[1] |
|
mouse intraperitoneal LD50 |
8141mg/kg[1] |
|
mouse intravenous LD50 |
6500mg/kg[1] |
|
mouse subcutaneous LD50 |
8750mg/kg[1] |
|
mouse oral LDLo |
18500mg/kg[1] |
|
rat intravenous LD50 |
11700mg/kg[1] |
|
rat oral LD50 |
17000mg/kg[1] |
|
rat intramuscular LDLo |
8400mg/kg[1] |
Reproductive effect[1].
Human Toxicity
Table 2 Human toxicity values
|
human oral LDLo |
5000mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent cleansing, antimicrobial, antibacterial, preservative, solubilizing, dispersing, lubricating abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Liquid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Liquid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as cleansing agent.
Use as solubilizing agent.
Use as lubricant.
Use as solvent.
Use as plasticizer; or used in synthesis of plasticizers.
Use as antimicrobial agent, preservative.
Use as viscosity reducer.
2, Personal care products
Viscosity controlling agent, masking agent in personal care products.
3, Organic synthesis
Use as intermediate in organic synthesis.
4, Polymer
Solvent in coatings, resins.
5, Industrial cleaning
Cleansing agent, solvent in industrial cleaning.
6, Textile
Solvent, lubricant in textile.
Manufacturers
References
[1]: ChemIDplus. 112-27-6, Triethylene glycol
Update: 20130928(1); 20200301(2);