Triclocarban
Synonyms
Carbanilide, 3,4,4'-trichloro-;
N-(4-Chlorophenyl)-N'-(3,4-dichlorophenyl)urea;
Category
Non-ionic surfactant
> Amide
>> Aromatic Amides
Chemical Numbering System
CAS: 101-20-2
EINECS: 202-924-1
Molecular Formula & Molecular Weight
Molecular Formula: C13H9Cl3N2O
Molecular Weight: 315.58
Structure
Properties
Appearance (1), solid.
Solubility slightly soluble in water.
Stability stable.
Risk Solid form: irritation, irritation to skin, eye, respiratory system.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
mouse intraperitoneal LD50 |
2100mg/kg[1] |
|
rabbit skin LD50 |
> 7.94mg/kg[1] |
|
rat oral LD50 |
> 34600mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent antimicrobial, antibacterial, preservative, dispersing abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as antimicrobial agent, antibacterial agent, preservative.
2, Personal care products
Preservative, deodorant in personal care products.
Further information:
(1), In accordance with Safety and Technical Standards for Cosmetics (2015 Edition) of China, be included in the allowable preservatives.
Maximum concentration is 0.2%.
Purity criteria: 3,3',4,4'-Tetrachloroazobenzene < 1mg/kg; 3,3',4,4'-Tetrachloroazoxybenzene < 1mg/kg.
(2), (2a), In accordance with EU regulations (EC) No 1223/2009, directive 86/199/EEC, be included in Annex V/23.
Maximum concentration is 0.2%.
Purity criteria: 3,3',4,4'-Tetrachloroazobenzene < 1ppm; 3,3',4,4'-Tetrachloroazoxybenzene < 1ppm.
(2b), In accordance with EU regulations (EC) No 1223/2009, directive 2007/17/EC, be included in Annex III/100.
Can be applied to rinse-off products.
Maximum concentration is 1.5%.
Purity criteria: 3,3',4,4'-Tetrachloroazobenzene <= 1ppm; 3,3',4,4'-Tetrachloroazoxybenzene <= 1ppm.
Manufacturers
References
[1]: ChemIDplus. 101-20-2, Triclocarban
Update: 20190811(1);