Phenolphthalein
Synonyms
1(3H)-Isobenzofuranone, 3,3-bis(4-hydroxyphenyl)-;
Category
Non-ionic surfactant
> Phenol
>> Ester-group Phenol
Chemical Numbering System
CAS: 77-09-8
EINECS: 201-004-7
Molecular Formula & Molecular Weight
Molecular Formula: C20H14O4
Molecular Weight: 318.32
Structure
Properties
Appearance (1), solid.
Solubility slightly soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
rat oral LD |
> 1000mg/kg[1] |
|
rat intraperitoneal LDLo |
500mg/kg[1] |
Human Toxicity
Table 2 Human toxicity values
|
man oral TDLo |
29mg/kg[1] |
Reasonably anticipated to be a human carcinogen[1].
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent dispersing, emulsifying abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), HG/T 4101 Chemical reagent -- Phenolphthalien
(1b), Chinese Pharmacopoeia (2015 Edition) Phenolphthalien
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as acid-base indicator.
Use as dispersing agent, emulsifying agent.
2, Medicine
Use as pharmaceutical ingredient (cathartica). (This section is for reference only, should be implemented according to local Pharmacopoeia.)
Manufacturers
References
[1]: ChemIDplus. 77-09-8, Phenolphthalein
Update: 20190908(1)