Vanillin
Synonyms
Benzaldehyde, 4-hydroxy-3-methoxy-;
FEMA No. 3107;
Category
Non-ionic surfactant
> Aldehyde
Chemical Numbering System
CAS: 121-33-5
EINECS: 204-465-2
Molecular Formula & Molecular Weight
Molecular Formula: C8H8O3
Molecular Weight: 152.15
Structure
Properties
Appearance (1), solid.
Odor pleasant vanilla odor.
Solubility soluble in water.
Physical - chemical properties
|
Water solubility, g/L |
11.02 (25°C)[1] |
Stability stable. Easily oxidized.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
dog intravenous LDLo |
1320mg/kg[2] |
|
guinea pig oral LD50 |
1400mg/kg[2] |
|
mouse inhalation LC |
> 41.7mg/kg/2[2] |
|
mouse intraperitoneal LD50 |
475mg/kg[2] |
|
mouse oral LD50 |
3925mg/kg[2] |
|
rabbit skin LD50 |
> 5010mg/kg[2] |
|
rabbit oral LDLo |
3000mg/kg[2] |
|
rat inhalation LC |
> 41.7mg/kg/4[2] |
|
rat skin LD |
> 2000mg/kg[2] |
|
rat intraperitoneal LD50 |
1160mg/kg[2] |
|
rat oral LD50 |
1580mg/kg[2] |
|
rat subcutaneous LD50 |
1500mg/kg[2] |
Reproductive effect[2].
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent anti-oxidizing, masking, dispersing abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), GB 1886.16 Food safety national standard -- Food additive -- Vanillin
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as perfume.
Use as antioxidant.
2, Personal care products
Masking agent in personal care products.
3, Food
Use as food additive (perfume).
Manufacturers
References
[1]: HSDB. 121-33-5, Vanillin
[2]: ChemIDplus. 121-33-5, Vanillin
Update: 20190825(1);