Prasterone
Synonyms
3beta-Hydroxyandrost-5-en-17-one;
Androst-5-en-17-one, 3-hydroxy-, (3-beta)-;
Category
Non-ionic surfactant
> Ketone
>> Alicyclic Ketones
Chemical Numbering System
CAS: 53-43-0
EINECS: 200-175-5
Molecular Formula & Molecular Weight
Molecular Formula: C19H28O2
Molecular Weight: 288.42
Structure
Properties
Appearance (1), solid.
Solubility slightly soluble in water.
Stability stable. Easily oxidized.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
mouse oral LD50 |
> 10000mg/kg[1] |
|
mouse subcutaneous LD50 |
900mg/kg[1] |
|
rat oral LD50 |
> 10000mg/kg[1] |
|
rat subcutaneous LD50 |
1000mg/kg[1] |
Reproductive effect[1].
Human Toxicity
Table 2 Human toxicity values
|
man oral TDLo |
10mg/kg/2W-I[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent emulsifying, dispersing abilities. Hormones.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as dispersing agent, emulsifying agent.
Manufacturers
References
[1]: ChemIDplus. 53-43-0, Prasterone
Update: 20190804(1);