Riboflavin
Synonyms
Vitamin B2;
Lactoflavin;
Category
Non-ionic surfactant
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>> Heteroaromatic Amine
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Chemical Numbering System
CAS: 83-88-5
EINECS: 201-507-1
Molecular Formula & Molecular Weight
Molecular Formula: C17H20N4O6
Molecular Weight: 376.36
Structure
Properties
Appearance (1), orange-yellow solid.
Solubility slightly soluble in water.
Stability stable. Unstable to alkali, light.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2, nitrogen oxides and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
dog oral LD |
> 2000mg/kg[1] |
|
rat intraperitoneal LD50 |
560mg/kg[1] |
|
rat intravenous LD50 |
50mg/kg[1] |
|
rat oral LD50 |
> 10000mg/kg[1] |
|
rat subcutaneous LD50 |
5000mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent antistatic, dispersing abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), GB/T 7297 Feed additive -- Vitamin B2 (riboflavin)
(1b), GB 14752 Food safety national standard -- Food additive -- Vitamin B2 (Riboflavin)
(1c), GB/T 18632 Feed additive -- 80% Riboflavin (vitamin B2) particle
(1d), Chinese Pharmacopoeia (2020 Edition) Vitamin B2
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as micronutrient.
Use as photosensitizing agent.
Use as antistatic agent.
2, Personal care products
Conditioning agent, colorant in personal care products.
Further information:
(1), In accordance with EU regulations (EC) 2009/1223, directive 88/667/EEC, be included in Annex IV/145.
(2), In accordance with Safety and Technical Standards for Cosmetics (2015 Edition) of China, be included in the allowable colorants.
Can be applied to all kinds of products.
3, Food
Use as food additive (colorant), food nutrition enhancer.
4, Feed
Use as feed additive.
5, Medicine
Use as pharmaceutical ingredient (vitamins). (This section is for reference only, should be implemented according to local Pharmacopoeia.)
Manufacturers
References
[1]: ChemIDplus. 83-88-5, Riboflavin
Update: 20200905(1);