Pyridoxine HCl
Synonyms
Pyridoxine hydrochloride;
Pyridoxol hydrochloride;
3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, hydrochloride (1:1);
Category
Non-ionic surfactant
> Amine
>> Heteroaromatic Amine
>>> Pyridine and its Derivatives
Chemical Numbering System
CAS: 58-56-0
EINECS: 200-386-2
Molecular Formula & Molecular Weight
Molecular Formula: C8H12ClNO3; C8H11N1O3.HCl
Molecular Weight: 205.64
Structure
Properties
Appearance (1), solid.
Solubility soluble in water.
Stability stable. Easily oxidized.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2, nitrogen oxides and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
cat intramuscular LD50 |
500mg/kg[1] |
|
cat intravenous LD50 |
560mg/kg[1] |
|
cat oral LD50 |
1000mg/kg[1] |
|
dog oral LD50 |
> 500mg/kg[1] |
|
mouse intravenous LD50 |
660mg/kg[1] |
|
mouse oral LD50 |
5500mg/kg[1] |
|
mouse subcutaneous LD50 |
2450mg/kg[1] |
|
pigeon intravenous LD50 |
145mg/kg[1] |
|
rabbit intravenous LD50 |
464mg/kg[1] |
|
rat intravenous LD50 |
530mg/kg[1] |
|
rat oral LD50 |
4000mg/kg[1] |
|
rat subcutaneous LD50 |
3000mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent antistatic, dispersing, emulsifying abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), GB 7298 Feed additive -- Vitamin B6 (pyridoxine hydrochloride)
(1b), GB 14753 Food safety national standard -- Food additive -- Vitamin B6 (pyridoxine hydrochloride)
(1c), Chinese Pharmacopoeia (2020 Edition) Vitamin B6
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as micronutrient.
Use as antistatic agent.
2, Personal care products
Conditioning agent, antistatic agent in personal care products.
3, Food
Use as food additive, food nutrition enhancer.
4, Feed
Use as feed additive.
5, Medicine
Use as pharmaceutical ingredient (vitamins). (This section is for reference only, should be implemented according to local Pharmacopoeia.)
Manufacturers
References
[1]: ChemIDplus. 58-56-0, Pyridoxine hydrochloride
Update: 20200905(1);