Pyrithione sodium
Synonyms
2(1H)-Pyridinethione, 1-hydroxy-, sodium salt;
Sodium Pyrithione;
Category
Anionic Surfactant
> Hydroxamic Acid and its Derivatives
Chemical Numbering System
CAS: 15922-78-8
EINECS: 240-062-8
Molecular Formula & Molecular Weight
Molecular Formula: C5H4NNaOS; C5H5N1O1S.Na
Molecular Weight: 149.15
Structure
Properties
Appearance (1), solid.
Solubility soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
dog intravenous LD |
> 50mg/kg[1] |
|
monkey intravenous LD |
> 50mg/kg[1] |
|
mouse intraperitoneal LD50 |
265mg/kg[1] |
|
mouse intravenous LD50 |
335mg/kg[1] |
|
mouse oral LD50 |
870mg/kg[1] |
|
mouse subcutaneous LD50 |
428mg/kg[1] |
|
rabbit intravenous LDLo |
200mg/kg[1] |
|
rat intraperitoneal LDLo |
385mg/kg[1] |
|
rat oral LDLo |
745mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent antimicrobial, antibacterial, preservative, dispersing abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as antimicrobial agent, antibacterial agent, preservative.
Manufacturers
References
[1]: ChemIDplus. 15922-78-8, Pyrithione sodium
Update: 20190401(1);