Lipase
Synonyms
Lipase, triacylglycerol;
Rizolipase;
EC 3.1.1.3;
Category
Special Surfactant
> Enzyme
Chemical Numbering System
CAS: 9001-62-1
EINECS: 232-619-9
Molecular Formula & Molecular Weight
Molecular Formula: N/A
Molecular Weight: N/A
Structure
Properties
Appearance (1), solid.
Solubility soluble in water.
Stability stable.
Risk Solid form: irritation, irritation to skin, eye, respiratory system.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
guinea pig intravenous LD50 |
135mg/kg[1] |
|
mouse oral LD |
> 10400mg/kg[1 |
|
mouse intraperitoneal LD50 |
395mg/kg[1] |
|
mouse intraperitoneal LD50 |
833mg/kg[1] |
|
mouse intravenous LD50 |
127mg/kg[1] |
|
mouse subcutaneous LD50 |
2050mg/kg[1] |
|
rabbit oral LD |
> 5000mg/kg[1] |
|
rat oral LD |
> 10400mg/kg[1] |
|
rat subcutaneous LD |
> 5000mg/kg[1] |
|
rat intraperitoneal LD50 |
630mg/kg[1] |
|
rat intraperitoneal LD50 |
634mg/kg[1] |
|
rat intravenous LD50 |
104mg/kg[1] |
Reproductive effect[1].
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent catalytic ability. Catalyze the hydrolysis of triglycerides.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Enzyme activity, U, ≥ |
|
Test Methods
(1), Enzyme activity
GB/T 23535 Lipase preparations
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Heavy metals (as Pb), mg/kg, ≤ |
30 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
GB 5009.74 Food safety national standard -- Method for limit test of heavy metals in food additives
GB 5009.12 Food safety national standard -- Determination of lead in foods
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
GB 5009.11 Food safety national standard -- Determination of total arsenic and abio-arsenic in foods
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), GB/T 23535 Lipase preparations
4, Further explanation
(a), Used in cosmetics, should be test for harmful substances; or furtherly test for microorganisms.
Major Uses
1, Typical applications
Use as catalyst.
2, Personal care products
Conditioning agent in personal care products.
3, Food
Use as food additive.
Manufacturers
References
[1]: ChemIDplus. 9001-62-1, Lipase
Update: 20180815(1);