Eugenol
Synonyms
Phenol, 2-methoxy-4-(2-propenyl)-;
FEMA No. 2467;
Category
Non-ionic surfactant
> Phenol
>> Ether-group Phenol
Chemical Numbering System
CAS: 97-53-0
EINECS: 202-589-1
Molecular Formula & Molecular Weight
Molecular Formula: C10H12O2
Molecular Weight: 164.20
Structure
Properties
Appearance (1), liquid.
Odor clove-like odor.
Solubility slightly soluble in water.
Physical - chemical properties
|
Water solubility, g/L |
2.46 (25°C)[1] |
Stability stable. Easily oxidized.
Risk Liquid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
dog oral LDLo |
500mg/kg[2] |
|
guinea pig oral LD50 |
2130mg/kg[2] |
|
hamster intraperitoneal LD50 |
17mg/kg[2] |
|
mouse intraperitoneal LD50 |
500mg/kg[2] |
|
mouse intravenous LD50 |
72mg/kg[2] |
|
mouse oral LD50 |
3000mg/kg[2] |
|
rat inhalation LC |
> 2580mg/m3/4H[2] |
|
rat intratracheal LD50 |
11mg/kg[2] |
|
rat oral LD50 |
1930mg/kg[2] |
|
rat intraperitoneal LDLo |
800mg/kg[2] |
|
rat subcutaneous LDLo |
5000mg/kg[2] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent masking, anti-oxidizing, anti-inflammatory, preservative, dispersing abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Liquid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Liquid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), GB 1886.129 Food safety national standard -- Food additive -- Eugenol
(1b), Chinese Pharmacopoeia (2015 Edition) Eugenol
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as perfume.
Use as antioxidant.
2, Personal care products
Perfume, denaturing agent, tonic in personal care products.
Further information:
(1), In accordance with EU regulations (EC) No 1223/2009, directive 2003/15/EC, be included in Annex III/71.
3, Food
Use as food additive (perfume).
4, Medicine
Pharmaceutical excipient, use as flavoring agent. (This section is for reference only, should be implemented according to local Pharmacopoeia.)
Manufacturers
References
[1]: HSDB. 97-53-0, Eugenol
[2]: ChemIDplus. 97-53-0, Eugenol
Update: 20190901(1)