Sodium pyrithione
Synonyms
2-Pyridinethiol, 1-oxide, sodium salt (1:1);
2-Pyridinethiol, N-oxide, sodium salt;
Pyrithione sodium;
Category
Zwitterionic Surfactant
> Amine Oxide
>> Heteroaromatic Amine Oxide
Chemical Numbering System
CAS: 3811-73-2
EINECS: 223-296-5
Molecular Formula & Molecular Weight
Molecular Formula: C5H4NNaOS
Molecular Weight: 149.15
Structure
Properties
Appearance (1), solid.
Solubility soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
mouse intraperitoneal LD50 |
370mg/kg[1] |
|
mouse intravenous LD50 |
320mg/kg[1] |
|
mouse oral LD50 |
870mg/kg[1] |
|
mouse subcutaneous LD50 |
428mg/kg[1] |
|
mouse parenteral LDLo |
800mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent antimicrobial, antibacterial, preservative abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as antimicrobial agent, preservative.
Manufacturers
References
[1]: ChemIDplus. 3811-73-2, Sodium pyrithione
Update: 20140729(1); 20190714(2);