Desoxycholic acid
Synonyms
Cholan-24-oic acid, 3,12-dihydroxy-, (3alpha,5beta,12alpha)-;
Deoxycholic acid;
Category
Anionic Surfactant
> Carboxylate
>> Chain Carboxylate
>>> Deoxycholic acid and Its Derivatives
Chemical Numbering System
CAS: 83-44-3
EINECS: 201-478-5
Molecular Formula & Molecular Weight
Molecular Formula: C24H40O4
Molecular Weight: 392.57
Structure
Properties
Appearance (1), solid.
Solubility slightly soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
mouse intravenous LD50 |
130mg/kg[1] |
|
mouse oral LD50 |
1000mg/kg[1] |
|
rabbit intravenous LDLo |
2000mg/kg[1] |
|
rat oral LD50 |
1000mg/kg[1] |
Reproductive effect[1].
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent emulsifying, dispersing, lubricating, solubilizing abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
GB/T 5173 Surface active agents and detergents -- Determination of anionic-active matter by direct two-phase titration procedure
ISO 2271 Surface active agents -- Detergents -- Determination of anionic-active matter by manual or mechanical direct two-phase titration procedure
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as emulsifying agent, dispersing agent.
Use as lubricant.
2, Organic synthesis
Use as intermediate in organic synthesis.
Manufacturers
References
[1]: ChemIDplus. 83-44-3, Deoxycholic acid
Update: 20140309(1); 20181008(2);