Sodium guaiazulene sulfonate
Synonyms
Sodium 5-isopropyl-3,8-dimethyl-1-azulene sulfonate;
Sodium gualenate;
Category
Anionic Surfactant
> Sulfonate
>> Aryl Sulfonate
>>> Bridge-ring Group Sulfonate
>>>> Linear Alkyl Bridge-ring Group Sulfonate
Chemical Numbering System
CAS: 6223-35-4
EINECS: 228-309-8
Molecular Formula & Molecular Weight
Molecular Formula: C15H17NaO3S; C15H18O3S.Na
Molecular Weight: 300.35
Structure
Properties
Appearance (1), solid.
Solubility soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
mouse intraperitoneal LD50 |
105mg/kg[1] |
|
mouse oral LD50 |
1540mg/kg[1] |
|
rat intraperitoneal LD50 |
180mg/kg[1] |
|
rat oral LD50 |
6380mg/kg[1] |
|
rat subcutaneous LD50 |
520mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent anti-inflammatory, anti-allergy, dispersing, emulsifying abilities.
Note (1), A sesquiterpenoid compound (azulene compound).
Synthesis
Guaiazulene and sulfur trioxide react, then obtain product.
Refer to:
China patent CN1803768A Process for the synthesis of 2-hydroxy-4-alkyloxy benzophenone, etc.
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
90.0 |
Test Methods
(1), Actives
GB/T 5173 Surface active agents and detergents -- Determination of anionic-active matter by direct two-phase titration procedure
ISO 2271 Surface active agents -- Detergents -- Determination of anionic-active matter by manual or mechanical direct two-phase titration procedure
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances; or furtherly test for microorganisms.
Major Uses
1, Typical applications
Use as anti-inflammatory ingredient.
2, Personal care products
Use as conditioning agent.
3, Medicine
Use as pharmaceutical ingredient (for example: anti-inflammatory ingredient). (Used in medicine, must comply with local pharmacopoeia execution.)
Manufacturers
References
[1]: ChemIDplus. 6223-35-4, Sodium gualenate
Update: 20131025(1); 20170425(2);