Sodium cyclamate
Synonyms
Sulfamic acid, N-cyclohexyl-, sodium salt (1:1);
Sulfamic acid, cyclohexyl-, monosodium salt;
Category
Zwitterionic Surfactant
> Sulfonate Type
>> Alicyclic Amine Sulfonate
Chemical Numbering System
CAS: 139-05-9
EINECS: 205-348-9
Molecular Formula & Molecular Weight
Molecular Formula: C6H12NNaO3S; C6H13N1O3S.Na
Molecular Weight: 201.22
Structure
Properties
Appearance (1), white solid.
Solubility soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2, nitrogen oxides and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
mouse intraperitoneal LD50 |
1154mg/kg[1] |
|
mouse intravenous LD50 |
4800mg/kg[1] |
|
mouse oral LD50 |
17000mg/kg[1] |
|
rat intraperitoneal LD50 |
1350mg/kg[1] |
|
rat intravenous LD50 |
3500mg/kg[1] |
|
rat oral LD50 |
1280mg/kg[1] |
Reproductive effect[1].
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent masking, dispersing, emulsifying abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), GB 1886.37 Food safety national standard -- Food additive -- Sodium cyclamate
(1b), Chinese Pharmacopoeia (2015 Edition) Sodium cyclamate
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as non-nutritive sweetener.
2, Personal care products
Masking agent in personal care products.
3, Food
Use as food additive (sweetener).
4, Medicine
Pharmaceutical excipient, use as sweetener, flavoring agent. (This section is for reference only, should be implemented according to local Pharmacopoeia.)
Manufacturers
References
[1]: ChemIDplus. 139-05-9, Sodium cyclamate
Update: 20140729(1); 20190721(2);