N,N-Diethyl-m-toluamide
Synonyms
Benzamide, N,N-diethyl-3-methyl-;
Diethyl toluamide;
DEET;
Category
Non-ionic surfactant
> Amide
>> Aromatic Amides
Chemical Numbering System
CAS: 134-62-3
EINECS: 205-149-7
Molecular Formula & Molecular Weight
Molecular Formula: C12H17NO; C12H17N1O
Molecular Weight: 191.27
Structure
Properties
Appearance (1), liquid.
Solubility slightly soluble in water.
Stability stable.
Risk Liquid form: flammable material; irritation, irritation to skin, eye. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
mouse oral LD50 |
1170mg/kg[1] |
|
mouse skin LD50 |
3.17mL/kg[1] |
|
rabbit oral LD50 |
1584mg/kg[1] |
|
rabbit skin LD50 |
3.18mL/kg[1] |
|
rabbit intravenous LDLo |
75mg/kg[1] |
|
rat inhalation LC50 |
5950mg/m3[1] |
|
rat oral LD50 |
1950mg/kg[1] |
|
rat skin LD50 |
5000mg/kg[1] |
Reproductive effect[1].
Human Toxicity
Table 2 Human toxicity values
|
child oral TDLo |
4750mg/kg[1] |
|
human skin TDLo |
35mg/kg/5D[1] |
|
man oral LDLo |
679mg/kg[1] |
|
women oral LDLo |
950mg/kg[1] |
|
women oral TDLo |
0.3mmg/kg[1] |
|
women oral TDLo |
950mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent dispersing, emulsifying abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Liquid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Liquid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as dispersing agent, emulsifying agent.
2, Personal care products
Conditioning agent, skin protective agent in personal care products.
3, Agriculture
Use as insect repellent, mosquito repellent.
Manufacturers
References
[1]: ChemIDplus. 134-62-3, Diethyltoluamide
Update: 20130917(1); 20190811(2);