beta-Cyclodextrin
Synonyms
β-Cyclodextrin;
Cycloheptapentylose;
Betadex;
Category
Polymer Surfactant
> Polysaccharide and its Derivatives
>> Non-ionic Polysaccharide and its Derivatives
Chemical Numbering System
CAS: 7585-39-9
EINECS: 231-493-2
Molecular Formula & Molecular Weight
Molecular Formula: N/A
Molecular Weight: N/A
Structure
Properties
Appearance (1), white powder.
Solubility soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
mouse intraperitoneal LD50 |
330mg/kg[1] |
|
mouse oral LD50 |
> 12500mg/kg[1] |
|
mouse subcutaneous LD50 |
412mg/kg[1] |
|
rat intraperitoneal LD50 |
356mg/kg[1] |
|
rat intravenous LD50 |
1008mg/kg[1] |
|
rat oral LD50 |
18800mg/kg[1] |
|
rat subcutaneous LD50 |
3700mg/kg[1] |
Reproductive effect[1].
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent emulsifying, dispersing, lubricating, masking abilities. Molecular wrapping material.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
80.0 |
Test Methods
(1), Actives
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), GB 1886.180 Food safety national standard -- Food additive -- beta-Cyclodextrin
(1b), Chinese Pharmacopoeia (2015 Edition) Betacyclodextrin
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as dispersing agent, emulsifying agent.
Use as molecular wrapping material.
Use as masking agent, deodorant.
Use as suspending agent.
Use as carrier.
2, Personal care products
Chelating agent, absorbing agent in personal care products.
3, Medicine
Pharmaceutical excipient, use as coating agent, stabilizer. (This section is for reference only, should be implemented according to local Pharmacopoeia.)
4, Food
Use as food additive (thickening agent, cholesterol extractant).
Manufacturers
References
[1]: ChemIDplus. 7585-39-9, beta-Cyclodextrin
Update: 20140911(1); 20200510(2);