D-Sorbitol
Synonyms
D-Glucitol;
Glucitol;
Sorbitol;
Category
Non-ionic surfactant
> Alcohol
>> Fatty Alcohol
Chemical Numbering System
CAS: 50-70-4
EINECS: 200-061-5
Molecular Formula & Molecular Weight
Molecular Formula: C6H14O6
Molecular Weight: 182.17
Structure
Properties
Appearance (1), white powder; (2), liquid.
Solubility soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
mouse intraperitoneal LD50 |
15000mg/kg[1] |
|
mouse intravenous LD50 |
9480mg/kg[1] |
|
mouse oral LD50 |
17800mg/kg[1] |
|
mouse subcutaneous LD50 |
24000mg/kg[1] |
|
rat intravenous LD50 |
7100mg/kg[1] |
|
rat oral LD50 |
15900mg/kg[1] |
|
rat subcutaneous LD50 |
29600mg/kg[1] |
Human Toxicity
Table 2 Human toxicity values
|
women oral TDLo |
1700mg/kg/D[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent dispersing, hydrotropic abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid / liquid |
|
|
Actives, %, ≥ |
95.0 / 70.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), GB 1886.187 Food safety national standard -- Food additive -- Sorbitol and sorbitol solution
(1b), GB/T 32097 Sorbitol and sorbitol solution for industry
(1c), QB/T 2335 Oral care and cleansing products -- Sorbitol solution for toothpaste
(1d), YY/T 0123 Medicinal intermediates -- D-Sorbitol solution
(1e), Chinese Pharmacopoeia (2015 Edition) Sorbitol
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as intermediate in organic synthesis.
Use as dispersing agent.
Use as plasticizer.
Use as flavor carrier.
Use as chelating agent.
2, Personal care products
Conditioning agent, humectant, plasticizer in personal care products.
3, Food
Use as food additive (sweetener, bulking agent, emulsifier, water retainer, stabilizer, thickener).
4, Medicine
Use as pharmaceutical ingredient (dehydrating agent). (This section is for reference only, should be implemented according to local Pharmacopoeia.)
Manufacturers
References
[1]: ChemIDplus. 50-70-4, Sorbitol
Update: 20130920(1); 20190915(2)