Ergocalciferol
Synonyms
Vitamin D2;
9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol,(3beta,5Z,7E,22E)-;
Category
Non-ionic surfactant
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>> Alicyclic Alcohol and its Derivatives
Chemical Numbering System
CAS: 50-14-6
EINECS: 200-014-9
Molecular Formula & Molecular Weight
Molecular Formula: C28H44O
Molecular Weight: 396.65
Structure
Properties
Appearance (1), crystal.
Solubility insoluble in water.
Stability stable. Easily oxidized.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
cat oral LDLo |
5mg/kg[1] |
|
dog intramuscular LDLo |
5mg/kg[1] |
|
dog intraperitoneal LDLo |
10mg/kg[1] |
|
dog intravenous LDLo |
5mg/kg[1] |
|
dog oral LDLo |
4mg/kg[1] |
|
duck oral LD50 |
> 2000mg/kg[1] |
|
guinea pig oral LD50 |
40mg/kg[1] |
|
mouse oral LD50 |
23.7mg/kg[1] |
|
rat oral LD50 |
10mg/kg[1] |
Reproductive effect[1].
Human Toxicity
Table 2 Human toxicity values
|
women oral TDLo |
12.6mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent dispersing, emulsifying, lubricating abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), GB 14755 Food additive -- Vitamin D2
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as dispersing agent, emulsifying agent.
Use as lubricant.
Use as intermediate in organic synthesis.
Use as vitamin.
2, Food
Use as food nutrition enhancer.
3, Medicine
Use as pharmaceutical ingredient (vitamin drugs). (This section is for reference only, should be implemented according to local Pharmacopoeia.)
Manufacturers
References
[1]: ChemIDplus. 50-14-6, Ergocalciferol
Update: 20130920(1); 20190922(2)