Disodium 5'-guanylate
Synonyms
5'-Guanylic acid, disodium salt;
5'-Guanylic acid, sodium salt (1:2);
Disodium guanylate;
Guanosine 5'-(disodium phosphate);
FEMA No. 3668;
Category
Zwitterionic Surfactant
> Phosphate Type
Chemical Numbering System
CAS: 5550-12-9
EINECS: 226-914-1
Molecular Formula & Molecular Weight
Molecular Formula: C10H12N5NaO8P; C10H14N5O8P.2Na
Molecular Weight: 407.18
Structure
Properties
Appearance (1), white crystal powder.
Solubility soluble in water.
Stability stable.
Risk Solid form: irritation, irritation to skin, eye, respiratory system.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
mouse intraperitoneal LD50 |
5010mg/kg[1] |
|
mouse intravenous LD50 |
3580mg/kg[1] |
|
mouse oral LD50 |
15000mg/kg[1] |
|
mouse subcutaneous LD50 |
5050mg/kg[1] |
|
rat intraperitoneal LD50 |
3880mg/kg[1] |
|
rat intravenous LD50 |
2720mg/kg[1] |
|
rat oral LD50 |
> 17300mg/kg[1] |
|
rat subcutaneous LD50 |
3400mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent emulsifying, dispersing, antistatic, anticorrosive, masking abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
90.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), GB 1886.170 Food safety national standard -- Food additive -- Disodium 5'-guanylate
(1b), QB/T 2846 Food additive -- Disodium 5'-guanylate
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as emulsifying agent, dispersing agent.
Use as masking agent.
2, Personal care products
Conditioning agent, emollient, humectant in personal care products. Good compatibility with skin.
3, Food
Use as food additive (flavor enhancer, perfume).
Manufacturers
References
[1]: ChemIDplus. 5550-12-9, Disodium 5'-guanylate
Update: 20140804(1); 20190701(2);