Camphor
Synonyms
DL-Camphor;
(+-)-Camphor;
Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-;
DL-Bornan-2-one;
FEMA No. 4513;
Category
Non-ionic surfactant
> Ketone
>> Alicyclic Ketones
Chemical Numbering System
CAS: 76-22-2
EINECS: 200-945-0
Molecular Formula & Molecular Weight
Molecular Formula: C10H16O
Molecular Weight: 152.23
Structure
Properties
Appearance (1), white crystal.
Odor stimulus odor.
Solubility slightly soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
rat intraperitoneal LDLo |
900mg/kg[1] |
|
mouse intraperitoneal LD50 |
3000mg/kg[1] |
|
rabbit oral LD50 |
2000mg/kg[1] |
|
cat intraperitoneal LDLo |
400mg/kg[1] |
|
dog oral LDLo |
800mg/kg[1] |
|
frog subcutaneous LDLo |
240mg/kg[1] |
|
mouse inhalation LCLo |
400mg/m3/3H[1] |
|
mouse oral LD50 |
1310mg/kg[1] |
|
mouse subcutaneous LDLo: |
200mg/kg[1] |
|
rat subcutaneous LD50 |
70mg/kg[1] |
Human Toxicity
Table 2 Human toxicity values
|
child oral TDLo |
51mg/kg[1] |
|
infant oral LDLo |
70mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent anti-inflammatory, antibacterial, preservative, anti-itch, dispersing, masking abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), GB/T 4895 Synthetic camphor
(1b), Chinese Pharmacopoeia (2015 Edition) Camphor (Racemic)
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as masking agent.
2, Personal care products
Masking agent, denaturing agent, plasticizer in personal care products.
3, Medicine
Use as pharmaceutical ingredient (dermerethistica). (This section is for reference only, should be implemented according to local Pharmacopoeia.)
4, Polymer
Use as plasticizer.
5, Agriculture
Use as insect repellent.
6, Forestry
Preservative in wood processing.
7, Organic synthesis
Use as intermediate in organic synthesis.
8, Food
Use as food additive (perfume).
Manufacturers
References
[1]: ChemIDplus. 76-22-2, Camphor
Update: 20130909(1); 20190804(2);