2,6-Di-tert-butyl-p-cresol
Synonyms
Butylated hydroxytoluene;
Phenol, 2,6-bis(1,1-dimethylethyl)-4-methyl-;
p-Cresol, 2,6-di-tert-butyl-;
FEMA No. 2184;
BHT;
Category
Non-ionic surfactant
> Phenol
>> Hydrocarbyl Phenol
Chemical Numbering System
CAS: 128-37-0
EINECS: 204-881-4
Molecular Formula & Molecular Weight
Molecular Formula: C15H24O
Molecular Weight: 220.35
Structure
Properties
Appearance (1), white to pale yellow powder.
Solubility insoluble in water.
Stability stable. Easily oxidized.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
rat oral LD50 |
890mg/kg[1] |
|
mouse intraperitoneal LD50 |
138mg/kg[1] |
|
mouse oral LD50 |
650mg/kg[1] |
|
mouse intravenous LD50 |
180mg/kg[1] |
|
cat oral LDLo |
940mg/kg[1] |
|
guinea pig oral LD50 |
10700mg/kg[1] |
|
rabbit oral LDLo |
2100mg/kg[1] |
Reproductive effect[1].
Human Toxicity
Table 2 Human toxicity values
|
women oral TDLo |
80mg/kg[1] |
Overall carcinogenic evaluation: Group 3[1].
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent anti-oxidizing, dispersing abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), GB 1900 Food additive -- Butylated hydroxytoluene
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as antioxidant. For example, used in food, rubber, petroleum, petrochemical, household cleaning products, personal care products.
2, Personal care products
Antioxidant, masking agent in personal care products.
3, Food
Use as food additive (antioxidant).
Manufacturers
References
[1]: ChemIDplus. 128-37-0, Butylated hydroxytoluene
Update: 20130916(1); 20190908(2)