1,3-Dioxane, 5-bromo-5-nitro-
Synonyms
5-Bromo-5-nitro-1,3-dioxane;
m-Dioxane, 5-bromo-5-nitro-;
Category
Non-ionic surfactant
> Ether
Chemical Numbering System
CAS: 30007-47-7
EINECS: 250-001-7
Molecular Formula & Molecular Weight
Molecular Formula: C4H6BrNO4; C4H6Br1N1O4
Molecular Weight: 212.00
Structure
Properties
Appearance (1), white to pale yellow powder.
Solubility soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
rat oral LD50 |
455mg/kg[1] |
|
rat intraperitoneal LD50 |
31mg/kg[1] |
|
mouse oral LD50 |
590mg/kg[1] |
|
rabbit subcutaneous LDLo |
500mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent antimicrobial, antibacterial, preservative abilities.
Note (1), Avoid formation of nitrosamines.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as antimicrobial agent, preservative.
2, Personal care products
Preservative in personal care products.
Further information:
(1), In accordance with Safety and Technical Standards for Cosmetics (2015 Edition) of China, be included in the allowed preservatives.
Can be applied to rinse-off products.
Maximum concentration is 0.1%.
Avoid formation of nitrosamines.
(2), In accordance with EU regulations (EC) No 1223/2009, directive 89/174/EEC, be included in Annex V/20.
Can be applied to rinse-off products.
Maximum concentration is 0.1%.
Avoid formation of nitrosamines.
Manufacturers
References
[1]: ChemIDplus. 30007-47-7, 5-Bromo-5-nitro-1,3-dioxane
Update: 20130918(1); 20190825(2)