Benzethonium chloride
Synonyms
Ammonium, benzyldimethyl(2-(2-(p-(1,1,3,3-tetramethylbutyl)phenoxy)ethoxy)ethyl)-, chloride;
Benzenemethanaminium, N,N-dimethyl-N-(2-(2-(4-(1,1,3,3-tetramethylbutyl)phenoxy)ethoxy)ethyl)-, chloride;
Category
Cationic surfactant
> Quaternary Ammonium Salt
>> Ether Quaternary Ammonium Salt
>>> Phenyl Ether Quaternary Ammonium Salt
>>>> Mono-(Branched Alkylphenyl Ether) Quaternary Ammonium Salt
Chemical Numbering System
CAS: 121-54-0
EINECS: 204-479-9
Molecular Formula & Molecular Weight
Molecular Formula: C27H42ClNO2; C27H42N1O2.Cl
Molecular Weight: 448.08
Structure
Properties
Appearance (1), white solid; or colorless to slightly yellow liquid.
Solubility soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, strong irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2, nitrogen oxides and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
rat oral LD50 |
368mg/kg[1] |
|
rat intraperitoneal LD50 |
16.5mg/kg[1] |
|
rat intravenous LD50 |
19mg/kg[1] |
|
rat subcutaneous LD50 |
119mg/kg[1] |
|
mouse oral LD50 |
338mg/kg[1] |
|
mouse intraperitoneal LD50 |
7.813mg/kg[1] |
|
mouse intravenous LD50 |
30mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent antistatic, antibacterial, antimicrobial, preservative, solubilizing, emulsifying, dispersing, wetting, permeating abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
GB/T 5174 Surface active agents -- Detergents -- Determination of cationic-active matter content
ISO 2871-1 Surface active agents -- Detergents -- Determination of cationic-active matter content -- Part 1: High-molecular-mass cationic-active matter
ISO 2871-2 Surface active agents -- Detergents -- Determination of cationic-active matter content -- Part 2: Cationic-active matter of low molecular mass (between 200 and 500)
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as disinfectant, antimicrobial agent, preservative.
Use as antistatic agent.
Use as emulsifying agent, dispersing agent.
Use as flocculant.
Use as deodorant.
2, Personal care products
Antimicrobial agent, preservative, deodorant in personal care products.
Further information:
(1), In accordance with Safety and Technical Standards for Cosmetics (2015 Edition) of China, be included in the allowable preservatives.
Maximum concentration is 0.1%.
(2), In accordance with EU regulations (EC) No 1223/2009, directive 2005/42/EC, be included in Annex V/53.
Maximum concentration is 0.1%.
Can be applied to leave-on products other than oral products and rinse-off products.
3, Agriculture
Emulsifying agent, dispersing agent, antimicrobial agent in pesticides.
4, Water treatment
Bactericide-algicide, slime stripping agent in water treatment.
5, Forestry
Antimicrobial agent, preservative in wood processing.
Manufacturers
References
[1]: ChemIDplus. 121-54-0, Benzethonium chloride
Update: 20140510(1); 20190609(2);