Adenine
Synonyms
Purine, 6-amino-;
9H-Purin-6-amine;
Category
Non-ionic surfactant
> Amine
>> Heteroaromatic Amine
>>> Purine and its Derivatives
Chemical Numbering System
CAS: 73-24-5
EINECS: 200-796-1
Molecular Formula & Molecular Weight
Molecular Formula: C5H5N5
Molecular Weight: 135.13
Structure
Properties
Appearance (1), white solid.
Solubility slightly soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2, nitrogen oxides and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
mouse intraperitoneal LD50 |
100mg/kg[1] |
|
mouse intravenous LD50 |
> 30mg/kg[1] |
|
mouse oral LD50 |
783mg/kg[1] |
|
mouse subcutaneous LDLo |
1000mg/kg[1] |
|
rat intraperitoneal LD50 |
198mg/kg[1] |
|
rat oral LD50 |
227mg/kg[1] |
Reproductive effect[1].
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent emulsifying, dispersing, anticorrosive, lubricating, antistatic abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), Chinese Pharmacopoeia (2020 Edition) Adenine
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as dispersing agent, emulsion stabilizer.
Use as anticorrosive agent.
Use as antistatic agent.
Use as intermediate in organic synthesis.
Use as plant growth regulator.
2, Personal care products
Conditioning agent in personal care products.
3, Medicine
Pharmaceutical excipient, use as cryoprotector. (This section is for reference only, should be implemented according to local Pharmacopoeia.).
Manufacturers
References
[1]: ChemIDplus. 73-24-5, Adenine
Update: 20130918(1); 20200830(2);