1-Dodecanol
Synonyms
Dodecanol;
Lauryl alcohol;
1-Dodecyl alcohol;
1-Hydroxydodecane;
FEMA No. 2617;
Category
Non-ionic surfactant
> Alcohol
>> Fatty Alcohol
Chemical Numbering System
CAS: 112-53-8
EINECS: 203-982-0
Molecular Formula & Molecular Weight
Molecular Formula: C12H26O
Molecular Weight: 186.33
Structure
Properties
Appearance (1), colorless liquid.
Odor specific aromatic odor. High concentration: unpleasant.
Solubility insoluble in water. Soluble in ethanol.
Physical - chemical properties
|
Water solubility, mg/L |
4 (25°C)[1] |
|
Melting point, °C |
24[1] |
Stability stable.
Risk Liquid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
rat oral LD50 |
> 12800mg/kg[2] |
|
guinea pig skin LD50 |
> 10mL/kg[2] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent emulsifying, dispersing, lubricating, solubilizing abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Liquid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Liquid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), GB/T 16451 Natural fatty alcohols
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as emulsifying agent, dispersing agent.
Use as lubricant. For example, used in metalworking fluids, plastics, resins.
Use as foam stabilizing agent.
Use as intermediate in organic synthesis.
Use as perfume.
2, Personal care products
Conditioning agent, emollient, viscosity controlling agent, emulsion stabilizer, emulsifying agent in personal care products.
3, Food
Use as food additive (perfume).
Manufacturers
References
[1]: HSDB. 112-53-8, 1-Dodecanol
[2]: ChemIDplus. 112-53-8, 1-Dodecanol
Update: 20130920(1); 20190915(2)