Glutathione
Synonyms
Glycine, L-gamma-glutamyl-L-cysteinyl-;
Glycine, N-(N-L-gamma-glutamyl-L-cysteinyl)-;
N-(N-L-gamma-Glutamyl-L-cysteinyl)glycine
Category
Zwitterionic Surfactant
> Amino Acid Type
>> Peptide and its Salts
Chemical Numbering System
CAS: 70-18-8
EINECS: 200-725-4
Molecular Formula & Molecular Weight
Molecular Formula: C10H17N3O6S
Molecular Weight: 307.32
Structure
Properties
Appearance (1), white to pale yellow powder.
Solubility soluble in water.
Stability stable. Easily oxidized.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
mouse intramuscular LD50 |
4000mg/kg[1] |
|
mouse intraperitoneal LD50 |
4020mg/kg[1] |
|
mouse intravenous LD50 |
2238mg/kg[1] |
|
mouse oral LD50 |
5000mg/kg[1] |
|
mouse subcutaneous LD50 |
5000mg/kg[1] |
|
rabbit intravenous LD50 |
> 2000mg/kg[1] |
Reproductive effect[1].
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent anti-oxidizing, emulsifying, dispersing, antistatic, wetting, permeating abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Personal care products
Conditioning agent, antioxidant in personal care products.
Good compatibility with skin. Easily absorbed. Good anti-aging, skin conservation effects.
2, Medicine
Use as pharmaceutical ingredient. (This section is for reference only, should be implemented according to local Pharmacopoeia.)
Manufacturers
References
[1]: ChemIDplus. 70-18-8, Glutathione
Update: 20140916(1); 20190121(2);