PEO

PEO

Synonyms

PEG;

Polyethylene glycol;

Polyethylene oxide;

Poly(oxy-1,2-ethanediyl), alpha-hydro-omega-hydroxy-;

Category

Non-ionic surfactant

> Polyether

>> Ethylene Oxide - Propylene Oxide Homopolymer and Copolymer

Chemical Numbering System

CAS: 25322-68-3

EINECS: 500-038-2

Molecular Formula & Molecular Weight

Molecular Formula: (C2H4O)n.H2O

Molecular Weight: N/A

Structure

Properties

Appearance    (1), white solid.

Solubility    soluble in water.

Stability    stable.

Risk    Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.

GHS label:  

Animal Toxicity

Table 1 Animal toxicity values

dog intravenous LDLo	3000mg/kg[1]
guinea pig oral LD50	15700mg/kg[1]
guinea pig oral LD50	17000mg/kg[1]
guinea pig oral LD50	19600mg/kg[1]
guinea pig oral LD50	22500mg/kg[1]
guinea pig oral LD50	28000mg/kg[1]
guinea pig oral LD50	28900mg/kg[1]
guinea pig oral LD50	50000mg/kg[1]
guinea pig oral LD500	50900mg/kg[1]
mouse intraperitoneal LD50	473mg/kg[1]
mouse intraperitoneal LD50	2000mg/kg[1]
mouse intraperitoneal LD50	7500mg/kg[1]
mouse intraperitoneal LD50	8000mg/kg[1]
mouse intravenous LD50	7.9mg/kg[1]
mouse intravenous LD50	8550mg/kg[1]
mouse intravenous LD50	16000mg/kg[1]
mouse oral LD50	28915mg/kg[1]
mouse oral LD50	31000mg/kg[1]
mouse oral LD50	34000mg/kg[1]
mouse oral LD50	36000mg/kg[1]
mouse subcutaneous LD50	18000mg/kg[1]
rabbit skin LD	> 1000mg/kg[1]
rabbit skin LD50	> 20mL/kg[1]
rabbit skin LD50	> 20000mg/kg[1]
rabbit intravenous LD50	8000mg/kg[1]
rabbit oral LD50	14000mg/kg[1]
rabbit oral LD50	17300mg/kg[1]
rabbit oral LD50	19000mg/kg[1]
rabbit oral LD50	26800mg/kg[1]
rabbit oral LD50	28900mg/kg[1]
rabbit oral LD50	76000mg/kg[1]
rat intraperitoneal LD50	6790mg/kg[1]
rat intraperitoneal LD50	9000mg/kg[1]
rat intraperitoneal LD50	9700mg/kg[1]
rat intraperitoneal LD50	9708mg/kg[1]
rat intraperitoneal LD50	12600mg/kg[1]
rat intraperitoneal LD50	14100mg/kg[1]
rat intraperitoneal LD50	15390mg/kg[1]
rat intraperitoneal LD50	15570mg/kg[1]
rat intraperitoneal LD50	16000mg/kg[1]
rat intraperitoneal LD50	17000mg/kg[1]
rat intraperitoneal LD50	17700mg/kg[1]
rat intravenous LD50	7130mg/kg[1]
rat intravenous LD50	7312mg/kg[1]
rat intravenous LD50	7500mg/kg[1]
rat intravenous LD50	13000mg/kg[1]
rat intravenous LDLo	3000mg/kg[1]
rat intravenous LDLo	22000mg/kg[1]
rat oral LD	> 4000mg/kg[1]
rat oral LD50	600mg/kg[1]
rat oral LD50	1054mg/kg[1]
rat oral LD50	> 4000mg/kg[1]
rat oral LD50	22000mg/kg[1]
rat oral LD50	27500mg/kg[1]
rat oral LD50	28000mg/kg[1]
rat oral LD50	30000mg/kg[1]
rat oral LD50	30200mg/kg[1]
rat oral LD50	31600mg/kg[1]
rat oral LD50	31640mg/kg[1]
rat oral LD50	32000mg/kg[1]
rat oral LD50	44200mg/kg[1]
rat oral LD50	45000mg/kg[1]
rat oral LD50	50000mg/kg[1]
rat oral LD50	> 50000mg/kg[1]
rat oral LD50	51200mg/kg[1]
rat oral LD50	51310mg/kg[1]
rat subcutaneous LD50	16000mg/kg[1]

Ecology    may be hazardous to environment. Water body should be given special attention.

Biodegradability    biodegradable.

Characteristics    excellent emulsifying, dispersing, solubilizing, lubricating, flocculating abilities. Performance is related to EO number. Water-soluble thermoplastic resin.

Note    (1), The by-product 1,4-dioxane is a possible carcinogen. Generally, can be acceptable when concentration of 1,4-dioxane is less than 30ppm or less.

(2), Be careful with using in children's products.

(3), "PEO" referred to in this article is the product with average molecular weight higher than 20000. For product with molecular weight no more than 20000, please refer to "Polyethylene glycol".

In section of "Product members": "PEG-n", n: EO number; "PEG n", n: average molecular weight.

Synthesis

Obtained by polymerization of ethylene oxide.

Quality Standards & Test Methods

1, Physical and chemical indexes

Item	Physical and chemical indexes
	Solid
Actives, %, ≥	95.0

Test Methods

(1), Actives

GB/T 13173 Surface active agents -- Detergents -- Testing methods

2, Hazardous substances indexes

Item	Hazardous substances indexes
	Solid
Heavy metals (as Pb), mg/kg, ≤	20
As, mg/kg, ≤	3

Test Methods

(1), Heavy metals (as Pb)

Safety and Technical Standards for Cosmetics (2015 Edition)

GB/T 30799 The test method of food detergents -- Determination of heavy metals

(2), As

Safety and Technical Standards for Cosmetics (2015 Edition)

GB/T 30797 The test method of food detergents -- Determination of total arsenic

3, Further explanation

(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.

(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.

Major Uses

1, Typical applications

Use as emulsifying agent, dispersing agent.

Use as solubilizing agent.

Use as lubricant.

Use as flocculating agent.

Use as thickening agent.

Use as adhesive.

2, Personal care products

Humectant, solvent, emulsion stabilizer, water retaining agent, viscosity controlling agent, anticaking agent, plasticizer in personal care products.

3, Organic synthesis

Use as intermediate in organic synthesis.

4, Textile

Sizing agent in textile.

5, Papermaking

Use as papermaking additive.

Product members

PEG-500;

PEG-800;

PEG-1M;

PEG-2M;

PEG-5M;

PEG-7M;

PEG-9M;

PEG-14M;

PEG-20M;

PEG-23M;

PEG-25M;

PEG-45M;

PEG-65M;

PEG-90M;

PEG-115M;

PEG-160M;

PEG-180M;

Manufacturers

 

References

[1]: ChemIDplus. 25322-68-3, Polyethylene glycol

Update: 20130928(1); 20200301(2);