Polypropylene glycol
Synonyms
PPG;
Polyoxypropylene;
Oxirane, methyl-, homopolymer;
Propane-1,2-diol, propoxylated;
Category
Non-ionic surfactant
> Polyether
>> Ethylene Oxide - Propylene Oxide Homopolymer and Copolymer
Chemical Numbering System
CAS: 25322-69-4
EINECS: 500-039-8
Molecular Formula & Molecular Weight
Molecular Formula: (C3H6O)n.H2O
Molecular Weight: N/A
Structure
Properties
Appearance (1), colorless transparent viscous oily liquid.
Solubility insoluble in water to soluble in water. Soluble in ethanol, toluene. Solubility is related to PO number. In general, when the average molecular weight is less than 600, it is soluble in water.
Stability stable.
Risk Liquid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
dog intravenous LDLo |
20mg/kg[1] |
|
mouse intraperitoneal LD50 |
113mg/kg[1] |
|
mouse intraperitoneal LD50 |
195mg/kg[1] |
|
mouse intraperitoneal LD50 |
700mg/kg[1] |
|
mouse intraperitoneal LD50 |
3600mg/kg[1] |
|
rabbit skin LD50 |
> 20mL/kg[1] |
|
rabbit skin LD50 |
20mL/kg[1] |
|
rabbit skin LD50 |
> 10000mg/kg[1] |
|
rabbit skin LD50 |
> 30000mg/kg[1] |
|
rat intraperitoneal LD50 |
0.23mL/kg[1] |
|
rat intraperitoneal LD50 |
0.46mL/kg[1] |
|
rat intraperitoneal LD50 |
4470mg/kg[1] |
|
rat intravenous LD50 |
0.1mL/kg[1] |
|
rat intravenous LD50 |
0.2mL/kg[1] |
|
rat intravenous LD50 |
710mg/kg[1] |
|
rat oral LD50 |
35.6mL/kg[1] |
|
rat oral LD50 |
56.6mL/kg[1] |
|
rat oral LD50 |
> 2000mg/kg[1] |
|
rat oral LD50 |
2150mg/kg[1] |
|
rat oral LD50 |
2410mg/kg[1] |
|
rat oral LD50 |
3750mg/kg[1] |
|
rat oral LD50 |
4190mg/kg[1] |
|
rat oral LD50 |
7250mg/kg[1] |
|
rat oral LD50 |
9760mg/kg[1] |
|
rat oral LD50 |
10334mg/kg[1] |
|
rat oral LD50 |
14800mg/kg[1] |
|
rat oral LD50 |
> 15000mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent emulsifying, dispersing, solubilizing, lubricating, wetting, permeating, antistatic, antifoaming, cleansing abilities. Performance is related to PO number. Excellent biocompatibility. Resistance to high temperature, low temperature.
Note (1), In section of "Product members": "PPG-n", n: PO number; "PPG n", n: average molecular weight.
Synthesis
Obtained by polymerization of methyloxirane.
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Liquid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Liquid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), HG/T 4309 Polypropylene glycol
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as emulsifying agent, dispersing agent.
Use as solubilizing agent.
Use as lubricant.
Use as antifoaming agent.
2, Personal care products
Conditioning agent, solvent in personal care products.
3, Organic synthesis
Use as intermediate in organic synthesis.
Intermediate in synthesis of polyurethane foam.
4, Machinery
Lubricant, defoaming agent, high-temperature lubricant in stamping oils, metalworking fluids.
5, Perfume
Solubilizing agent in perfume.
6, Polymer
Defoaming agent, lubricant, antistatic agent, softening agent, plasticizer in rubber, resin, latex.
7, Textile
Antistatic agent, softening agent in textile, chemical fiber.
Product members
PPG-3;
PPG-7;
PPG-9;
PPG-12;
PPG-13;
PPG-15;
PPG-16;
PPG-17;
PPG-20;
PPG-26;
PPG-30;
PPG-33;
PPG-34;
PPG-51;
PPG-69;
PPG 150;
PPG 400;
PPG 425;
PPG 750;
PPG 1000;
PPG 1025;
PPG 1200;
PPG 1800;
PPG 2025;
PPG 3025;
PPG 4025;
Manufacturers
References
[1]: ChemIDplus. 25322-69-4, Polypropylene glycol
Update: 20130929(1); 20200301(2);