Diethylene Glycol Monoethyl Ether
Synonyms
2-(2-Ethoxyethoxy)ethanol;
Carbitol;
Ethanol, 2-(2-ethoxyethoxy)-;
Ethoxydiglycol;
2-(2-Ethoxyethoxy) ethanol;
3,6-Dioxa-1-octanol;
Category
Non-ionic surfactant
> Polyether
>> Alcohol Polyether
>>> Alcohol Polyoxyethylene Ether
>>>> Linear Alkanol Polyoxyethylene Ether
Chemical Numbering System
CAS: 111-90-0
EINECS: 203-919-7
Molecular Formula & Molecular Weight
Molecular Formula: C6H14O3
Molecular Weight: 134.17
Structure
Properties
Appearance (1), colorless transparent liquid.
Solubility soluble in water.
Stability stable.
Risk Liquid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
cat intravenous LDLo |
1000mg/kg[1] |
|
dog intravenous LD50 |
3mL/kg[1] |
|
guinea pig oral LD50 |
3.7mL/kg[1] |
|
guinea pig skin LD50 |
> 32000mg/kg[1] |
|
mouse intraperitoneal LD50 |
2300mg/kg[1] |
|
mouse intravenous LD50 |
4.3mL/kg[1] |
|
mouse oral LD50 |
6.6mL/kg[1] |
|
mouse skin LD50 |
6mL/kg[1] |
|
mouse subcutaneous LD50 |
5.5mL/kg[1] |
|
rabbit intravenous LD50 |
2.5mL/kg[1] |
|
rabbit oral LD50 |
3620mg/kg[1] |
|
rabbit skin LD50 |
4.2mL/kg[1] |
|
rat inhalation LC50 |
> 5240mg/m3/4H[1] |
|
rat intraperitoneal LD50 |
0.36mg/kg[1] |
|
rat intravenous LD50 |
4000mg/kg[1] |
|
rat oral LD50 |
5.5mL/kg[1] |
|
rat skin LD50 |
6mL/kg[1] |
|
rat subcutaneous LD50 |
6000mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent cleansing, dispersing, solubilizing, wetting, permeating abilities.
Note (1), The by-product 1,4-dioxane is a possible carcinogen. Generally, can be acceptable when concentration of 1,4-dioxane is less than 30ppm or less.
(2), Be careful with using in children's products.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Liquid |
|
|
Actives, %, ≥ |
95.0 |
|
pH (25°C, 1% solution) |
5.0 - 7.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
(2), pH
GB/T 6368 Surface active agents -- Determination of pH of aqueous solution -- Potentiometric method
ISO 4316 Surface active agents -- Determination of pH of aqueous solutions -- Potentiometric method
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Liquid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as solvent. For example, used in perfume, dye, coatings.
Use as cleansing agent. For example, used in household cleaning, industrial cleaning.
Use as solubilizing agent.
2, Industrial cleaning
Cleansing agent, paint remover in industrial cleaning.
3, Vehicle
Use as brake fluid component.
4, Organic synthesis
Use as intermediate in organic synthesis.
5, Personal care products
Solvent, masking agent, viscosity controlling agent in personal care products.
Further information:
(1), In accordance with EU regulations (EC) No 2016/314, be included in Annex III/297.
Can be applied to:
(1a), Oxidative hair dye products, maximum concentration is 7%.
(1b), Non-oxidative hair dye products, maximum concentration is 5%.
(1c), Rinse-off products other than hair dye products, maximum concentration is 10%.
(1d), Other non-spray cosmetic products, maximum concentration is 2.6%.
(1e), Spray products (fine fragrances, hair sprays, antiperspirant and deodorant), maximum concentration is 2.6%.
The level of ethylene glycol impurity in Ethoxydiglycol must be ≤ 0.1%.
Not to be used in eye products and oral products.
Manufacturers
References
[1]: ChemIDplus. 111-90-0, Diethylene glycol monoethyl ether
Update: 20130928(1); 20191021(2);