Butyrolactone
Synonyms
2(3H)-Furanone, dihydro-;
gamma-Butyrolactone;
FEMA No. 3291;
Category
Non-ionic surfactant
> Ester
>> Lactones
Chemical Numbering System
CAS: 96-48-0
EINECS: 202-509-5
Molecular Formula & Molecular Weight
Molecular Formula: C4H6O2
Molecular Weight: 86.09
Structure
Properties
Appearance (1), liquid.
Odor weak pleasant odor.
Solubility soluble in water.
Stability stable. Under strong alkali condition, easily hydrolyzed.
Risk Liquid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
guinea pig skin LD50 |
> 5000mg/kg[1] |
|
mouse intraperitoneal LD50 |
1100mg/kg[1] |
|
mouse oral LD50 |
1460mg/kg[1] |
|
mouse parenteral LDLo |
1600mg/kg[1] |
|
rabbit intravenous LDLo |
500mg/kg[1] |
|
rat inhalation LC50 |
> 5100mg/m3/4H[1] |
|
rat intraperitoneal LD50 |
1000mg/kg[1] |
|
rat oral LD50 |
1540mg/kg[1] |
Reproductive effect[1].
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent cleansing, dispersing abilities. High boiling solvent.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Liquid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Liquid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), HG/T 4989 γ-Butyrolactone for industrial use
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as solvent.
2, Personal care products
Solvent, masking agent in personal care products.
3, Industrial cleaning
Cleansing agent, paint remover in industrial cleaning.
4, Organic synthesis
Use as intermediate in organic synthesis.
5, Food
Use as food additive (perfume).
Manufacturers
References
[1]: ChemIDplus. 96-48-0, gamma-Butyrolactone
Update: 20141016(1); 20200412(2);