Diethyl phthalate
Synonyms
1,2-Benzenedicarboxylic acid, 1,2-diethyl ester;
1,2-Benzenedicarboxylic acid, diethyl ester;
Phthalic acid, diethyl ester;
Category
Non-ionic surfactant
> Ester
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Chemical Numbering System
CAS: 84-66-2
EINECS: 201-550-6
Molecular Formula & Molecular Weight
Molecular Formula: C12H14O4
Molecular Weight: 222.24
Structure
Properties
Appearance (1), liquid.
Solubility slightly soluble in water. Soluble in ethanol, ethyl ether.
Physical - chemical properties
|
Water solubility, g/L |
1.08 (25 °C)[1] |
Stability stable. Under strong acid or strong alkali condition, easily hydrolyzed.
Risk Liquid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
guinea pig oral LD50 |
8600mg/kg[2] |
|
guinea pig subcutaneous LD50 |
3000mg/kg[2] |
|
mouse intraperitoneal LD50 |
2749mg/kg[2] |
|
mouse oral LD50 |
6172mg/kg[2] |
|
rabbit oral LD50 |
1000mg/kg[2] |
|
rabbit intravenous LDLo |
100mg/kg[2] |
|
rat intraperitoneal LD50 |
5.058mL/kg[2] |
|
rat oral LD50 |
8600mg/kg[2] |
Reproductive effect[2].
Human Toxicity
Table 2 Human toxicity values
|
human inhalation TCLo |
1000mg/m3[2] |
|
man oral TDLo |
0.357mL/kg[2] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent cleansing, dispersing, emulsifying, solubilizing abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Liquid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Liquid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as plasticizer.
Use as solvent. For example, used in paints, resins.
Use as dispersing agent, emulsion stabilizer.
2, Personal care products
Film-forming agent, plasticizer, masking agent, solvent, conditioning agent, denaturant in personal care products.
3, Industrial cleaning
Cleansing agent, paint remover in industrial cleaning.
Manufacturers
References
[1]: HSDB. 84-66-2, Diethyl phthalate
[2]: ChemIDplus. 84-66-2, Diethyl phthalate
Update: 20141031(1); 20200614(2);