Phenylephrine hydrochloride
Synonyms
Benzenemethanol, 3-hydroxy-alpha-((methylamino)methyl)-, hydrochloride (1:1), (R)-;
(R)-Phenylephrine hydrochloride;
(-)-Phenylephrine hydrochloride;
L-Phenylephrine hydrochloride;
Category
Cationic surfactant
> Amine Salt
>> Secondary Amine Salt
>>> Aliphatic Secondary Amine Salt
>>>> Aryl Aliphatic Secondary Amine Salt
Chemical Numbering System
CAS: 61-76-7
EINECS: 200-517-3
Molecular Formula & Molecular Weight
Molecular Formula: C9H14ClNO2; C9H13NO2.HCl
Molecular Weight: 203.67
Structure
Properties
Appearance (1), solid.
Solubility soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent emulsifying, dispersing, antistatic abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), Chinese Pharmacopoeia (2020 Edition) Phenylephrine Hydrochloride
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as emulsifying agent, dispersing agent.
2, Medicine
Use as pharmaceutical ingredient (alpha-adrenoceptor agonists). (This section is for reference only, should be implemented according to local Pharmacopoeia.)
Manufacturers