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Thiostrepton

Time: 2025-02-23 22:29:43; Count: 6

Thiostrepton

Synonyms

Bryamycin;

Thiactin;

Category

Non-ionic surfactant

> Amine

>> Peptide and its Derivatives

Chemical Numbering System

CAS: 1393-48-2

EINECS: 215-734-9

Molecular Formula & Molecular Weight

Molecular Formula: C72H85N19O18S5

Molecular Weight: 1664.89

Structure

Properties

Appearance    (1), solid.

Solubility    insoluble in water.

Stability    stable.

Risk    Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.

GHS label:  

Ecology    may be hazardous to environment. Water body should be given special attention.

Biodegradability    biodegradable.

Characteristics    excellent antibacterial, antimicrobial abilities. Natural cyclic oligopeptide antibiotic. Thiazole antibiotics. Derived from streptomycetes, such as Streptomyces laurentii and Streptomyces azureus. Antibacterial activity is achieved by inhibiting the synthesis of bacterial proteins. Has anti-tumor effect.

Synthesis

 

Quality Standards & Test Methods

1, Physical and chemical indexes

Item

Physical and chemical indexes

Solid

Actives, %, ≥

90.0

Test Methods

(1), Actives

GB/T 13173 Surface active agents -- Detergents -- Testing methods

2, Hazardous substances indexes

Item

Hazardous substances indexes

Solid

Heavy metals (as Pb), mg/kg, ≤

20

As, mg/kg, ≤

3

Test Methods

(1), Heavy metals (as Pb)

Safety and Technical Standards for Cosmetics (2015 Edition)

GB/T 30799 The test method of food detergents -- Determination of heavy metals

(2), As

Safety and Technical Standards for Cosmetics (2015 Edition)

GB/T 30797 The test method of food detergents -- Determination of total arsenic

3, Further explanation

(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.

Major Uses

1, Typical applications

Use as antibacterial agent.

Use as pharmaceutical ingredient (antibiotic). (For reference only.)

Manufacturers

 

Article

[Terminology] Dispersion system

[Terminology] Vesicle

Pandect of Ester surfactants (1): Definition

[Terminology] Van Der Waals force

[Terminology] Micellar aggregation number

Standard

Test methods of surfactants, catalog, Chinese national standards

Surfactants, catalog, Chinese national standards