Thiostrepton
Synonyms
Bryamycin;
Thiactin;
Category
Non-ionic surfactant
> Amine
>> Peptide and its Derivatives
Chemical Numbering System
CAS: 1393-48-2
EINECS: 215-734-9
Molecular Formula & Molecular Weight
Molecular Formula: C72H85N19O18S5
Molecular Weight: 1664.89
Structure
Properties
Appearance (1), solid.
Solubility insoluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label:
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent antibacterial, antimicrobial abilities. Natural cyclic oligopeptide antibiotic. Thiazole antibiotics. Derived from streptomycetes, such as Streptomyces laurentii and Streptomyces azureus. Antibacterial activity is achieved by inhibiting the synthesis of bacterial proteins. Has anti-tumor effect.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
Item |
Physical and chemical indexes |
Solid |
|
Actives, %, ≥ |
90.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
Item |
Hazardous substances indexes |
Solid |
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
Major Uses
1, Typical applications
Use as antibacterial agent.
Use as pharmaceutical ingredient (antibiotic). (For reference only.)
Manufacturers