Sodium calcium edetate
Synonyms
Ethylene diamine tetraacetic acid, disodium calcium salt;
Calcium disodium EDTA;
Calcium disodium ethylenediamine tetraacetic acid;
Disodium calcium EDTA;
Category
Zwitterionic Surfactant
> Nitrilo Acid Type
>> Aliphatic Nitrilo Acid and its Salts
Chemical Numbering System
CAS: 62-33-9
EINECS: 200-529-9
Molecular Formula & Molecular Weight
Molecular Formula: C10H12CaN2Na2O8; C10H16N2O8.Ca.2Na
Molecular Weight: 374.27
Structure
Properties
Appearance (1), white to pale yellow powder or flake.
Solubility soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2, nitrogen oxides and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
rat oral LD50 |
10000mg/kg[1] |
|
rat intravenous LD50 |
3000mg/kg[1] |
|
rat intraperitoneal LD50 |
3850mg/kg[1] |
|
mouse oral LD50 |
10000mg/kg[1] |
|
mouse intraperitoneal LD50 |
4500mg/kg[1] |
|
rabbit intraperitoneal LD50 |
6000mg/kg[1] |
|
rabbit oral LD50 |
7000mg/kg[1] |
|
rabbit intravenous LDLo |
4000mg/kg[1] |
|
dog oral LD50 |
12000mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent chelating, dispersing, antistatic abilities.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), Chinese Pharmacopoeia (2015 Edition) Calcium Disodium Edetate*
*: hexahydrate.
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as chelating agent.
2, Personal care products
Chelating agent in personal care products.
3, Food
Use as food additive (antioxidant).
4, Coatings
Color retaining agent in paint.
5, Medicine
Use as pharmaceutical ingredient (heavy metal antidote). (This section is for reference only, should be implemented according to local Pharmacopoeia.)
Manufacturers
References
[1]: ChemIDplus. 62-33-9, Sodium calcium edetate
Update: 20140309(1); 20190506(2);