Calcium pantothenate, D-form
Synonyms
Pantothenic acid, calcium salt (2:1), D-;
Calcium pantothenate;
Calcium D-pantothenate;
Pantothenic acid, calcium salt (2:1), (+)-;
beta-Alanine, N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, calcium salt (2:1), (R)-;
Category
Anionic Surfactant
> Carboxylate
>> Acyl Amino Acid Salt
>>> Fatty Acyl Amino Acid Salt
>>> Hydroxy Branched Alkyl Acyl Amino Acid Salt
Chemical Numbering System
CAS: 137-08-6
EINECS: 205-278-9
Molecular Formula & Molecular Weight
Molecular Formula: C18H32CaN2O10; C9H17N1O5.1/2Ca
Molecular Weight: 476.53
Structure
Properties
Appearance (1), white to pale yellow powder.
Solubility soluble in water.
Stability stable.
Risk Solid form: flammable material; irritation, irritation to skin, eye, respiratory system. Harmful products of combustion are CO, CO2 and so on. Contact with strong oxidants, can cause to burn.
GHS label: 
Animal Toxicity
Table 1 Animal toxicity values
|
rat oral LD50 |
>10000mg/kg[1] |
|
rat intravenous LD50 |
830mg/kg[1] |
|
rat intraperitoneal LD50 |
820mg/kg[1] |
|
mouse oral LD50 |
10000mg/kg[1] |
|
mouse intravenous LD50 |
910mg/kg[1] |
|
mouse intraperitoneal LD50 |
920mg/kg[1] |
Ecology may be hazardous to environment. Water body should be given special attention.
Biodegradability biodegradable.
Characteristics excellent emulsifying, dispersing, wetting, lubricating abilities. Vitamin B family. Growth substance. Micronutrient.
Synthesis
Quality Standards & Test Methods
1, Physical and chemical indexes
|
Item |
Physical and chemical indexes |
|
Solid |
|
|
Actives, %, ≥ |
95.0 |
Test Methods
(1), Actives
GB/T 13173 Surface active agents -- Detergents -- Testing methods
2, Hazardous substances indexes
|
Item |
Hazardous substances indexes |
|
Solid |
|
|
Heavy metals (as Pb), mg/kg, ≤ |
20 |
|
As, mg/kg, ≤ |
3 |
Test Methods
(1), Heavy metals (as Pb)
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30799 The test method of food detergents -- Determination of heavy metals
(2), As
Safety and Technical Standards for Cosmetics (2015 Edition)
GB/T 30797 The test method of food detergents -- Determination of total arsenic
3, Product standards
(1), Chinese standards
(1a), GB/T 7299 Feed additive -- Dextro calcium pantothenate
(1b), Chinese Pharmacopoeia (2015 Edition) Calcium pantothenate
4, Further explanation
(a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight.
(b), Used in cosmetics, should be test for harmful substances or furtherly test for microorganisms, according to local regulations and standards.
Major Uses
1, Typical applications
Use as emulsifying agent, dispersing agent.
2, Personal care products
Conditioning agent, antistatic agent in personal care products. Good compatibility with skin, hair.
3, Food
Use as food nutritive fortifier.
4, Feed
Use as feed additive.
5, Medicine
Use as pharmaceutical ingredient (Vitamin drug). (This section is for reference only, should be implemented according to local Pharmacopoeia.)
Manufacturers
References
[1]: ChemIDplus. 137-08-6, Calcium pantothenate
Update: 20140209(1); 20181224(2);